node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
cu1358 | cu1477 | cu1358 | cu1477 | Putative membrane protein. | ACT domain-containing protein; Unnamed protein product. | 0.677 |
cu1476 | cu1477 | cu1476 | cu1477 | Hypothetical protein. | ACT domain-containing protein; Unnamed protein product. | 0.712 |
cu1476 | cu1478 | cu1476 | cu1478 | Hypothetical protein. | Cytochrome c oxidase subunit I; Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B. | 0.601 |
cu1477 | cu1358 | cu1477 | cu1358 | ACT domain-containing protein; Unnamed protein product. | Putative membrane protein. | 0.677 |
cu1477 | cu1476 | cu1477 | cu1476 | ACT domain-containing protein; Unnamed protein product. | Hypothetical protein. | 0.712 |
cu1477 | cu1478 | cu1477 | cu1478 | ACT domain-containing protein; Unnamed protein product. | Cytochrome c oxidase subunit I; Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B. | 0.693 |
cu1477 | cu1558 | cu1477 | cu1558 | ACT domain-containing protein; Unnamed protein product. | Phosphoserine transaminase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine. | 0.991 |
cu1477 | cu1593 | cu1477 | cu1593 | ACT domain-containing protein; Unnamed protein product. | Unnamed protein product. | 0.849 |
cu1477 | glyA | cu1477 | cu0604 | ACT domain-containing protein; Unnamed protein product. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.944 |
cu1477 | ilvA | cu1477 | cu0732 | ACT domain-containing protein; Unnamed protein product. | L-threonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | 0.908 |
cu1477 | metXA | cu1477 | cu0422 | ACT domain-containing protein; Unnamed protein product. | Homoserine O-acetyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine. | 0.801 |
cu1477 | trpA | cu1477 | cu1163 | ACT domain-containing protein; Unnamed protein product. | Tryptophan synthase alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.902 |
cu1477 | trpB | cu1477 | cu1164 | ACT domain-containing protein; Unnamed protein product. | Tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.914 |
cu1478 | cu1476 | cu1478 | cu1476 | Cytochrome c oxidase subunit I; Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B. | Hypothetical protein. | 0.601 |
cu1478 | cu1477 | cu1478 | cu1477 | Cytochrome c oxidase subunit I; Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B. | ACT domain-containing protein; Unnamed protein product. | 0.693 |
cu1558 | cu1477 | cu1558 | cu1477 | Phosphoserine transaminase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine. | ACT domain-containing protein; Unnamed protein product. | 0.991 |
cu1558 | glyA | cu1558 | cu0604 | Phosphoserine transaminase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.667 |
cu1593 | cu1477 | cu1593 | cu1477 | Unnamed protein product. | ACT domain-containing protein; Unnamed protein product. | 0.849 |
cu1593 | glyA | cu1593 | cu0604 | Unnamed protein product. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.880 |
cu1593 | ilvA | cu1593 | cu0732 | Unnamed protein product. | L-threonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | 0.807 |