STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
fhsFormate-tetrahydrofolate ligase; Belongs to the formate--tetrahydrofolate ligase family. (555 aa)    
Predicted Functional Partners:
folD
Methylenetetrahydrofolate dehydrogenase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate.
 
 
 0.995
GAL90416.1
IMP cyclohydrolase; Belongs to the PurH family.
  
 0.973
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
  
 0.949
GAL90923.1
Phosphoribosylformylglycinamidine synthase synthetase subunit.
  
 
 0.945
GAL90751.1
Aminomethyltransferase; Belongs to the GcvT family.
  
 0.924
GAL88193.1
5-methyltetrahydrofolate-homocysteine methyltransferase.
    
 0.904
GAL87959.1
Dihydrofolate reductase.
  
 
 0.902
GAL88191.1
5-methyltetrahydrofolate-homocysteine methyltransferase.
  
 
 0.893
purN
Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.
  
 0.800
GAL90619.1
Phosphoribosylglycinamide formyltransferase.
  
 0.800
Your Current Organism:
Jejuia pallidilutea
NCBI taxonomy Id: 504487
Other names: DSM 21165, Gaetbulibacter sp. EM39, J. pallidilutea, Jejuia pallidilutea Lee et al. 2009 emend. Park et al 2013, KCTC 22298, strain EM39
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