STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GAL89186.1Porphobilinogen synthase; Belongs to the ALAD family. (329 aa)    
Predicted Functional Partners:
GAL89193.1
Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.
 
 0.999
GAL89722.1
Glutamate-1-semialdehyde aminotransferase.
 
 
 0.990
GAL88186.1
uroporphyrinogen-III methyltransferase.
 
 
 0.915
hemA
glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
 
  
 0.868
hemE
Uroporphyrinogen III decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
 
 
 0.835
GAL88311.1
uroporphyrinogen-III synthase HemD.
  
 0.794
atpD
ATP synthase beta chain; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.
 
    
 0.760
GAL89187.1
Coproporphyrinogen III oxidase.
 
  
 0.757
GAL89185.1
Magnesium and cobalt efflux protein CorC.
  
    0.717
GAL89184.1
methylated-DNA-protein-cysteine methyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
       0.711
Your Current Organism:
Jejuia pallidilutea
NCBI taxonomy Id: 504487
Other names: DSM 21165, Gaetbulibacter sp. EM39, J. pallidilutea, Jejuia pallidilutea Lee et al. 2009 emend. Park et al 2013, KCTC 22298, strain EM39
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