node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AGK03426.1 | AGK03427.1 | K649_00570 | K649_00575 | COG0640 Predicted transcriptional regulators. | COG0477 Permeases of the major facilitator superfamily. | 0.538 |
AGK03426.1 | hisG | K649_00570 | K649_00580 | COG0640 Predicted transcriptional regulators. | ATP phosphoribosyltransferase catalytic subunit; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Short subfamily. | 0.423 |
AGK03427.1 | AGK03426.1 | K649_00575 | K649_00570 | COG0477 Permeases of the major facilitator superfamily. | COG0640 Predicted transcriptional regulators. | 0.538 |
AGK03427.1 | AGK03429.1 | K649_00575 | K649_00585 | COG0477 Permeases of the major facilitator superfamily. | COG0667 Predicted oxidoreductases (related to aryl-alcohol dehydrogenases). | 0.442 |
AGK03427.1 | AGK04370.1 | K649_00575 | K649_05340 | COG0477 Permeases of the major facilitator superfamily. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.458 |
AGK03427.1 | AGK04690.1 | K649_00575 | K649_06950 | COG0477 Permeases of the major facilitator superfamily. | N-acetyltransferase GCN5; COG0456 Acetyltransferases. | 0.420 |
AGK03427.1 | AGK06126.1 | K649_00575 | K649_14200 | COG0477 Permeases of the major facilitator superfamily. | COG0318 Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II. | 0.421 |
AGK03427.1 | hisG | K649_00575 | K649_00580 | COG0477 Permeases of the major facilitator superfamily. | ATP phosphoribosyltransferase catalytic subunit; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Short subfamily. | 0.592 |
AGK03429.1 | AGK03427.1 | K649_00585 | K649_00575 | COG0667 Predicted oxidoreductases (related to aryl-alcohol dehydrogenases). | COG0477 Permeases of the major facilitator superfamily. | 0.442 |
AGK03429.1 | hisG | K649_00585 | K649_00580 | COG0667 Predicted oxidoreductases (related to aryl-alcohol dehydrogenases). | ATP phosphoribosyltransferase catalytic subunit; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Short subfamily. | 0.572 |
AGK04370.1 | AGK03427.1 | K649_05340 | K649_00575 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | COG0477 Permeases of the major facilitator superfamily. | 0.458 |
AGK04370.1 | hisG | K649_05340 | K649_00580 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | ATP phosphoribosyltransferase catalytic subunit; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Short subfamily. | 0.450 |
AGK04690.1 | AGK03427.1 | K649_06950 | K649_00575 | N-acetyltransferase GCN5; COG0456 Acetyltransferases. | COG0477 Permeases of the major facilitator superfamily. | 0.420 |
AGK06126.1 | AGK03427.1 | K649_14200 | K649_00575 | COG0318 Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II. | COG0477 Permeases of the major facilitator superfamily. | 0.421 |
hisG | AGK03426.1 | K649_00580 | K649_00570 | ATP phosphoribosyltransferase catalytic subunit; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Short subfamily. | COG0640 Predicted transcriptional regulators. | 0.423 |
hisG | AGK03427.1 | K649_00580 | K649_00575 | ATP phosphoribosyltransferase catalytic subunit; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Short subfamily. | COG0477 Permeases of the major facilitator superfamily. | 0.592 |
hisG | AGK03429.1 | K649_00580 | K649_00585 | ATP phosphoribosyltransferase catalytic subunit; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Short subfamily. | COG0667 Predicted oxidoreductases (related to aryl-alcohol dehydrogenases). | 0.572 |
hisG | AGK04370.1 | K649_00580 | K649_05340 | ATP phosphoribosyltransferase catalytic subunit; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Short subfamily. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.450 |