STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nrdIRibonucleotide reductase stimulatory protein; Probably involved in ribonucleotide reductase function. (126 aa)    
Predicted Functional Partners:
AGK04198.1
COG0208 Ribonucleotide reductase, beta subunit.
 
 0.999
AGK04199.1
Ribonucleotide-diphosphate reductase subunit alpha; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
 
  
 0.991
AGK05706.1
Ribonucleoside-diphosphate reductase adenosylcobalamin-dependent; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.
  
  
 0.812
AGK03564.1
COG0695 Glutaredoxin and related proteins.
  
  
 0.727
AGK06031.1
Glutaredoxin; COG0526 Thiol-disulfide isomerase and thioredoxins.
  
  
 0.727
AGK04196.1
Thioesterase superfamily protein; COG1607 Acyl-CoA hydrolase.
       0.569
adk
Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.
     
 0.490
AGK04197.1
5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family.
       0.459
cobD
Cobalamin biosynthesis protein CobD; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
       0.431
Your Current Organism:
Meiothermus ruber
NCBI taxonomy Id: 504728
Other names: M. ruber DSM 1279, Meiothermus ruber ATCC 35948, Meiothermus ruber DSM 1279
Server load: low (12%) [HD]