STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AGK05346.1Restriction modification system DNA specificity domain-containing protein; COG0732 Restriction endonuclease S subunits. (419 aa)    
Predicted Functional Partners:
AGK05345.1
Adenine-specific DNA-methyltransferase; COG0286 Type I restriction-modification system methyltransferase subunit.
 
 
 0.999
AGK05348.1
Type I site-specific deoxyribonuclease HsdR family protein; Subunit R is required for both nuclease and ATPase activities, but not for modification.
 
  
 0.994
AGK04471.1
COG1002 Type II restriction enzyme, methylase subunits.
  
 
 0.981
AGK05347.1
Hypothetical protein; COG1943 Transposase and inactivated derivatives.
       0.782
AGK05513.1
DNA polymerase I; COG0258 5'-3' exonuclease (including N-terminal domain of PolI).
   
 
 0.607
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
  
   0.491
AGK05344.1
COG3684 Tagatose-1,6-bisphosphate aldolase.
       0.463
Your Current Organism:
Meiothermus ruber
NCBI taxonomy Id: 504728
Other names: M. ruber DSM 1279, Meiothermus ruber ATCC 35948, Meiothermus ruber DSM 1279
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