STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AGK05710.1COG1501 Alpha-glucosidases, family 31 of glycosyl hydrolases; Belongs to the glycosyl hydrolase 31 family. (762 aa)    
Predicted Functional Partners:
AGK05095.1
Putative esterase; COG2819 Predicted hydrolase of the alpha/beta superfamily.
   
  0.848
AGK04893.1
COG0296 1,4-alpha-glucan branching enzyme; Belongs to the glycosyl hydrolase 13 family.
 
  
 0.820
AGK04345.1
Alpha amylase; COG0366 Glycosidases.
 
  
 0.819
AGK04988.1
COG3345 Alpha-galactosidase.
 
  
 0.817
AGK03447.1
COG2214 DnaJ-class molecular chaperone.
   
   0.813
dnaJ
Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...]
   
   0.813
AGK04352.1
COG1640 4-alpha-glucanotransferase.
    
 0.811
AGK05705.1
Alpha amylase; COG0366 Glycosidases.
    
 0.796
AGK04458.1
Aconitate hydratase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate.
    
   0.768
AGK05086.1
Trehalose synthase; COG0366 Glycosidases.
    
 0.742
Your Current Organism:
Meiothermus ruber
NCBI taxonomy Id: 504728
Other names: M. ruber DSM 1279, Meiothermus ruber ATCC 35948, Meiothermus ruber DSM 1279
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.