node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SDH55516.1 | SDH76829.1 | SAMN05421871_101462 | SAMN05421871_1027 | 2-oxoglutarate decarboxylase. | Fumarate hydratase, class I; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | 0.955 |
SDH55516.1 | SDH79881.1 | SAMN05421871_101462 | SAMN05421871_102155 | 2-oxoglutarate decarboxylase. | Glutamate synthase (NADPH/NADH) large chain. | 0.974 |
SDH55516.1 | SDH82407.1 | SAMN05421871_101462 | SAMN05421871_102269 | 2-oxoglutarate decarboxylase. | Glutamate synthase (NADPH/NADH) large chain. | 0.974 |
SDH55516.1 | SDH94002.1 | SAMN05421871_101462 | SAMN05421871_102867 | 2-oxoglutarate decarboxylase. | Dihydrolipoamide dehydrogenase. | 0.999 |
SDH55516.1 | gcvH | SAMN05421871_101462 | SAMN05421871_102241 | 2-oxoglutarate decarboxylase. | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | 0.966 |
SDH55516.1 | gcvP | SAMN05421871_101462 | SAMN05421871_102522 | 2-oxoglutarate decarboxylase. | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.995 |
SDH55516.1 | gcvT | SAMN05421871_101462 | SAMN05421871_102240 | 2-oxoglutarate decarboxylase. | Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine. | 0.964 |
SDH55516.1 | glyA | SAMN05421871_101462 | SAMN05421871_102242 | 2-oxoglutarate decarboxylase. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.811 |
SDH55516.1 | glyA-2 | SAMN05421871_101462 | SAMN05421871_11410 | 2-oxoglutarate decarboxylase. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.811 |
SDH76829.1 | SDH55516.1 | SAMN05421871_1027 | SAMN05421871_101462 | Fumarate hydratase, class I; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | 2-oxoglutarate decarboxylase. | 0.955 |
SDH76829.1 | gcvP | SAMN05421871_1027 | SAMN05421871_102522 | Fumarate hydratase, class I; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.968 |
SDH79881.1 | SDH55516.1 | SAMN05421871_102155 | SAMN05421871_101462 | Glutamate synthase (NADPH/NADH) large chain. | 2-oxoglutarate decarboxylase. | 0.974 |
SDH79881.1 | SDH82407.1 | SAMN05421871_102155 | SAMN05421871_102269 | Glutamate synthase (NADPH/NADH) large chain. | Glutamate synthase (NADPH/NADH) large chain. | 0.999 |
SDH79881.1 | SDH94002.1 | SAMN05421871_102155 | SAMN05421871_102867 | Glutamate synthase (NADPH/NADH) large chain. | Dihydrolipoamide dehydrogenase. | 0.880 |
SDH79881.1 | gcvH | SAMN05421871_102155 | SAMN05421871_102241 | Glutamate synthase (NADPH/NADH) large chain. | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | 0.941 |
SDH79881.1 | gcvP | SAMN05421871_102155 | SAMN05421871_102522 | Glutamate synthase (NADPH/NADH) large chain. | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.978 |
SDH79881.1 | gcvT | SAMN05421871_102155 | SAMN05421871_102240 | Glutamate synthase (NADPH/NADH) large chain. | Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine. | 0.954 |
SDH79881.1 | glyA | SAMN05421871_102155 | SAMN05421871_102242 | Glutamate synthase (NADPH/NADH) large chain. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.876 |
SDH79881.1 | glyA-2 | SAMN05421871_102155 | SAMN05421871_11410 | Glutamate synthase (NADPH/NADH) large chain. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.876 |
SDH79881.1 | purD | SAMN05421871_102155 | SAMN05421871_106194 | Glutamate synthase (NADPH/NADH) large chain. | Phosphoribosylamine--glycine ligase; Belongs to the GARS family. | 0.529 |