STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SDI53347.1DNA ligase D. (316 aa)    
Predicted Functional Partners:
SDJ43509.1
Bifunctional non-homologous end joining protein LigD.
  
 0.992
SDJ17989.1
ATP-dependent DNA ligase.
  
 0.954
ku
DNA end-binding protein Ku; With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD. Belongs to the prokaryotic Ku family.
 
  
 0.886
lig
DNA ligase-1; DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair.
  
 0.845
SDI53320.1
Hypothetical protein.
       0.773
SDJ43487.1
Bifunctional non-homologous end joining protein LigD.
 
  
 
0.709
SDI39132.1
Bifunctional non-homologous end joining protein LigD.
 
  
 
0.700
SDH92511.1
Exodeoxyribonuclease-3.
 
 
    0.658
menC
O-succinylbenzoate synthase; Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB).
       0.565
SDH91977.1
Exodeoxyribonuclease-3.
 
 
    0.469
Your Current Organism:
Alloactinosynnema album
NCBI taxonomy Id: 504798
Other names: A. album, Alloactinosynnema album Yuan et al. 2010, Amycolatopsis sp. 03-9939, CCM 7461, DSM 45114, JCM 17965, KCTC 19294, strain 03-9939
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