STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SDI59074.1Dynamin family protein. (610 aa)    
Predicted Functional Partners:
SDI59053.1
GrpE protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...]
 
     0.961
SDI58991.1
Dynamin family protein.
 
     0.906
SDH95576.1
Hsp70 protein; Belongs to the heat shock protein 70 family.
 
     0.778
SDH95597.1
Hsp70 protein.
 
     0.777
SDH78621.1
Hypothetical protein.
  
     0.761
SDI57808.1
Hypothetical protein.
  
     0.761
SDH63804.1
Type VII secretion protein EccE.
  
     0.760
SDH63588.1
Type VII secretion-associated protein, Rv3446c family, C-terminal domain-containing protein; Belongs to the heat shock protein 70 family.
 
     0.758
SDI61036.1
Hypothetical protein.
  
     0.757
SDH62158.1
Anti-sigma-D factor RsdA to sigma factor binding region.
  
     0.750
Your Current Organism:
Alloactinosynnema album
NCBI taxonomy Id: 504798
Other names: A. album, Alloactinosynnema album Yuan et al. 2010, Amycolatopsis sp. 03-9939, CCM 7461, DSM 45114, JCM 17965, KCTC 19294, strain 03-9939
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