STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
SDI85253.1Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. (1124 aa)    
Predicted Functional Partners:
SDI07487.1
Urea carboxylase.
  
 0.974
pckG
Phosphoenolpyruvate carboxykinase (GTP); Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle; Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.
   
 
 0.967
SDI51193.1
Citrate synthase; Belongs to the citrate synthase family.
  
 0.963
SDH62823.1
acetyl-CoA carboxylase carboxyl transferase subunit beta.
 
 0.952
SDH80051.1
Pyruvate kinase; Belongs to the pyruvate kinase family.
   
 0.950
mdh
Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family.
  
 0.945
SDI51380.1
Citrate synthase; Belongs to the citrate synthase family.
  
 0.939
SDH66423.1
2-oxoglutarate ferredoxin oxidoreductase subunit alpha.
     
 0.917
SDH58624.1
BirA family transcriptional regulator, biotin operon repressor / biotin-[acetyl-CoA-carboxylase] ligase.
 
 
 0.910
SDI19565.1
Acetyl/propionyl-CoA carboxylase, alpha subunit.
 
0.909
Your Current Organism:
Alloactinosynnema album
NCBI taxonomy Id: 504798
Other names: A. album, Alloactinosynnema album Yuan et al. 2010, Amycolatopsis sp. 03-9939, CCM 7461, DSM 45114, JCM 17965, KCTC 19294, strain 03-9939
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