node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SDG23029.1 | SDG56434.1 | SAMN05421505_102329 | SAMN05421505_105181 | Glutamine synthetase. | Ammonium transporter, Amt family. | 0.721 |
SDG23029.1 | SDG56466.1 | SAMN05421505_102329 | SAMN05421505_105182 | Glutamine synthetase. | Nitrogen regulatory protein P-II family. | 0.776 |
SDG23029.1 | SDG80200.1 | SAMN05421505_102329 | SAMN05421505_10873 | Glutamine synthetase. | Glutamate synthase (NADPH/NADH) large chain. | 0.986 |
SDG23029.1 | SDH03137.1 | SAMN05421505_102329 | SAMN05421505_110172 | Glutamine synthetase. | Cyclic nucleotide-binding domain-containing protein. | 0.589 |
SDG23029.1 | SDI20540.1 | SAMN05421505_102329 | SAMN05421505_13824 | Glutamine synthetase. | Glutamine synthetase. | 0.878 |
SDG23029.1 | glnD | SAMN05421505_102329 | SAMN05421505_105183 | Glutamine synthetase. | [protein-PII] uridylyltransferase; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism. | 0.723 |
SDG23029.1 | glnE | SAMN05421505_102329 | SAMN05421505_102336 | Glutamine synthetase. | Glutamate-ammonia-ligase adenylyltransferase; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transd [...] | 0.785 |
SDG23029.1 | nadE | SAMN05421505_102329 | SAMN05421505_102326 | Glutamine synthetase. | NAD+ synthase (glutamine-hydrolysing); Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.745 |
SDG56434.1 | SDG23029.1 | SAMN05421505_105181 | SAMN05421505_102329 | Ammonium transporter, Amt family. | Glutamine synthetase. | 0.721 |
SDG56434.1 | SDG56466.1 | SAMN05421505_105181 | SAMN05421505_105182 | Ammonium transporter, Amt family. | Nitrogen regulatory protein P-II family. | 0.999 |
SDG56434.1 | SDG80200.1 | SAMN05421505_105181 | SAMN05421505_10873 | Ammonium transporter, Amt family. | Glutamate synthase (NADPH/NADH) large chain. | 0.930 |
SDG56434.1 | SDH03137.1 | SAMN05421505_105181 | SAMN05421505_110172 | Ammonium transporter, Amt family. | Cyclic nucleotide-binding domain-containing protein. | 0.887 |
SDG56434.1 | SDI20540.1 | SAMN05421505_105181 | SAMN05421505_13824 | Ammonium transporter, Amt family. | Glutamine synthetase. | 0.784 |
SDG56434.1 | glnD | SAMN05421505_105181 | SAMN05421505_105183 | Ammonium transporter, Amt family. | [protein-PII] uridylyltransferase; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism. | 0.929 |
SDG56434.1 | glnE | SAMN05421505_105181 | SAMN05421505_102336 | Ammonium transporter, Amt family. | Glutamate-ammonia-ligase adenylyltransferase; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transd [...] | 0.561 |
SDG56434.1 | nadE | SAMN05421505_105181 | SAMN05421505_102326 | Ammonium transporter, Amt family. | NAD+ synthase (glutamine-hydrolysing); Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.542 |
SDG56466.1 | SDG23029.1 | SAMN05421505_105182 | SAMN05421505_102329 | Nitrogen regulatory protein P-II family. | Glutamine synthetase. | 0.776 |
SDG56466.1 | SDG56434.1 | SAMN05421505_105182 | SAMN05421505_105181 | Nitrogen regulatory protein P-II family. | Ammonium transporter, Amt family. | 0.999 |
SDG56466.1 | SDG80200.1 | SAMN05421505_105182 | SAMN05421505_10873 | Nitrogen regulatory protein P-II family. | Glutamate synthase (NADPH/NADH) large chain. | 0.857 |
SDG56466.1 | SDH03137.1 | SAMN05421505_105182 | SAMN05421505_110172 | Nitrogen regulatory protein P-II family. | Cyclic nucleotide-binding domain-containing protein. | 0.989 |