SDH27603.1 protein (Sinosporangium album) - STRING interaction network

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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co-expression

protein homology

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Score

SDH27603.1

ATP-binding cassette, subfamily B/ATP-binding cassette, subfamily C. (618 aa)

Predicted Functional Partners:

SDG16700.1

0.899

SDI47357.1

0.804

SDH27678.1

0.652

SDH95965.1

0.634

SDH35227.1

0.587

SDH72402.1

0.570

SDG75593.1

0.540

SDH28096.1

0.523

SDH28081.1

0.520

SDH00575.1

0.511

Your Current Organism:

Sinosporangium album

NCBI taxonomy Id: 504805
Other names: DSM 45181, KCTC 19655, S. album, Sinosporangium album Zang et al. 2011, Streptosporangineae bacterium 6014, strain 6014

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
SDG16700.1	SDH27603.1	SAMN05421505_102126	SAMN05421505_113110	Glutamate transport system ATP-binding protein.	ATP-binding cassette, subfamily B/ATP-binding cassette, subfamily C.	0.899
SDG75593.1	SDH27603.1	SAMN05421505_107195	SAMN05421505_113110	Acyl transferase domain-containing protein.	ATP-binding cassette, subfamily B/ATP-binding cassette, subfamily C.	0.540
SDG75593.1	SDH27678.1	SAMN05421505_107195	SAMN05421505_113111	Acyl transferase domain-containing protein.	AMP-binding enzyme.	0.862
SDG75593.1	SDH95965.1	SAMN05421505_107195	SAMN05421505_12826	Acyl transferase domain-containing protein.	Nonribosomal peptide synthetase DhbF.	0.999
SDG75593.1	SDI47357.1	SAMN05421505_107195	SAMN05421505_1563	Acyl transferase domain-containing protein.	Acyl transferase domain-containing protein.	0.999
SDH00575.1	SDH27603.1	SAMN05421505_11083	SAMN05421505_113110	ATPase family associated with various cellular activities (AAA); Belongs to the AAA ATPase family.	ATP-binding cassette, subfamily B/ATP-binding cassette, subfamily C.	0.511
SDH00575.1	SDI47357.1	SAMN05421505_11083	SAMN05421505_1563	ATPase family associated with various cellular activities (AAA); Belongs to the AAA ATPase family.	Acyl transferase domain-containing protein.	0.403
SDH27603.1	SDG16700.1	SAMN05421505_113110	SAMN05421505_102126	ATP-binding cassette, subfamily B/ATP-binding cassette, subfamily C.	Glutamate transport system ATP-binding protein.	0.899
SDH27603.1	SDG75593.1	SAMN05421505_113110	SAMN05421505_107195	ATP-binding cassette, subfamily B/ATP-binding cassette, subfamily C.	Acyl transferase domain-containing protein.	0.540
SDH27603.1	SDH00575.1	SAMN05421505_113110	SAMN05421505_11083	ATP-binding cassette, subfamily B/ATP-binding cassette, subfamily C.	ATPase family associated with various cellular activities (AAA); Belongs to the AAA ATPase family.	0.511
SDH27603.1	SDH27678.1	SAMN05421505_113110	SAMN05421505_113111	ATP-binding cassette, subfamily B/ATP-binding cassette, subfamily C.	AMP-binding enzyme.	0.652
SDH27603.1	SDH28081.1	SAMN05421505_113110	SAMN05421505_113130	ATP-binding cassette, subfamily B/ATP-binding cassette, subfamily C.	NHLM bacteriocin system ABC transporter, peptidase/ATP-binding protein.	0.520
SDH27603.1	SDH28096.1	SAMN05421505_113110	SAMN05421505_113131	ATP-binding cassette, subfamily B/ATP-binding cassette, subfamily C.	NHLM bacteriocin system ABC transporter, ATP-binding protein.	0.523
SDH27603.1	SDH35227.1	SAMN05421505_113110	SAMN05421505_114118	ATP-binding cassette, subfamily B/ATP-binding cassette, subfamily C.	Calcineurin-like phosphoesterase.	0.587
SDH27603.1	SDH72402.1	SAMN05421505_113110	SAMN05421505_12121	ATP-binding cassette, subfamily B/ATP-binding cassette, subfamily C.	Polar amino acid transport system ATP-binding protein.	0.570
SDH27603.1	SDH95965.1	SAMN05421505_113110	SAMN05421505_12826	ATP-binding cassette, subfamily B/ATP-binding cassette, subfamily C.	Nonribosomal peptide synthetase DhbF.	0.634
SDH27603.1	SDI47357.1	SAMN05421505_113110	SAMN05421505_1563	ATP-binding cassette, subfamily B/ATP-binding cassette, subfamily C.	Acyl transferase domain-containing protein.	0.804
SDH27678.1	SDG75593.1	SAMN05421505_113111	SAMN05421505_107195	AMP-binding enzyme.	Acyl transferase domain-containing protein.	0.862
SDH27678.1	SDH27603.1	SAMN05421505_113111	SAMN05421505_113110	AMP-binding enzyme.	ATP-binding cassette, subfamily B/ATP-binding cassette, subfamily C.	0.652
SDH27678.1	SDH95965.1	SAMN05421505_113111	SAMN05421505_12826	AMP-binding enzyme.	Nonribosomal peptide synthetase DhbF.	0.986

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Network Stats

number of nodes:

4

number of edges:

4

average node degree:

2

avg. local clustering coefficient:

0.833

expected number of edges:

4

PPI enrichment p-value:

0.461

your network does not have significantly more
interactions than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0044205

De novo UMP biosynthetic process

7 of 9

2.13

4.62

4.39e-11

GO:0009064

Glutamine family amino acid metabolic process

7 of 14

1.94

4.01

1.36e-10

GO:0009156

Ribonucleoside monophosphate biosynthetic process

9 of 34

1.66

3.36

2.81e-11

GO:0006541

Glutamine metabolic process

5 of 11

1.9

2.92

2.07e-07

GO:0009084

Glutamine family amino acid biosynthetic process

4 of 5

2.14

2.87

1.40e-06

(more ...)

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0004088

Carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity

3 of 4

2.11

1.59

0.00084

GO:0016884

Carbon-nitrogen ligase activity, with glutamine as amido-N-donor

4 of 16

1.64

1.39

0.00084

GO:0016879

Ligase activity, forming carbon-nitrogen bonds

5 of 37

1.37

1.2

0.00084

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0005737

Cytoplasm

11 of 672

0.45

0.37

0.0010

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:1014

Ribonucleoside monophosphate metabolic process, and Pteridine-containing compound metabolic process

11 of 53

1.56

3.43

1.03e-14

CL:1089

UMP metabolic process, and Bifunctional protein PyrR

5 of 12

1.86

2.58

1.39e-06

CL:1091

De novo UMP biosynthetic process, and Xanthine/uracil permease

4 of 7

2.0

2.31

1.63e-05

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map00250

Alanine, aspartate and glutamate metabolism

8 of 21

1.82

3.92

1.57e-11

map00240

Pyrimidine metabolism

7 of 43

1.45

2.17

8.29e-08

map00220

Arginine biosynthesis

2 of 3

2.06

1.12

0.0075

map01100

Metabolic pathways

11 of 612

0.49

0.42

0.00014

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0005727

Extrachromosomal circular DNA

2 of 2

2.24

0.78

0.0370

GOCC:0005622

Intracellular

10 of 711

0.39

0.27

0.0370

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0665

Pyrimidine biosynthesis

7 of 10

2.08

4.48

5.41e-11

KW-0055

Arginine biosynthesis

3 of 3

2.24

1.91

0.00022

KW-0315

Glutamine amidotransferase

3 of 10

1.72

1.33

0.0016

KW-0436

Ligase

5 of 60

1.16

1.01

0.00081

KW-0464

Manganese

2 of 9

1.59

0.69

0.0425

Protein Domains (SMART)

domain

description

count in network

strength

signal

false discovery rate

SM01096

Carbamoyl-phosphate synthetase large chain, oligomerisation domain

2 of 2

2.24

1.01

0.0136

SM00851

MGS-like domain

2 of 3

2.06

0.99

0.0136

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