STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SDI34147.1methylated-DNA-[protein]-cysteine S-methyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated. (210 aa)    
Predicted Functional Partners:
SDI34175.1
RNA polymerase sigma factor, sigma-70 family; Belongs to the sigma-70 factor family. ECF subfamily.
 
     0.932
SDI33919.1
Alkylated DNA repair protein (DNA oxidative demethylase).
 
  
 0.889
SDI33972.1
Metal binding domain of Ada.
 
     0.860
SDI34068.1
Hypothetical protein.
 
     0.844
SDG66458.1
AraC family transcriptional regulator, regulatory protein of adaptative response / DNA-3-methyladenine glycosylase II.
 
 
 0.801
SDI33888.1
DNA-3-methyladenine glycosylase I.
       0.790
SDI33950.1
Hypothetical protein.
       0.777
SDI34205.1
methylated-DNA-[protein]-cysteine S-methyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
 
    
0.723
SDG53165.1
Deoxyribodipyrimidine photo-lyase; Belongs to the DNA photolyase family.
     
 0.420
Your Current Organism:
Sinosporangium album
NCBI taxonomy Id: 504805
Other names: DSM 45181, KCTC 19655, S. album, Sinosporangium album Zang et al. 2011, Streptosporangineae bacterium 6014, strain 6014
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.