STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hemHFerrochelatase HemH; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family. (348 aa)    
Predicted Functional Partners:
hemE
Uroporphyrinogen decarboxylase HemE; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
 
  
 0.945
AEI07040.1
Putative amine oxidase.
  
 
 0.939
AEI07718.1
Hypothetical protein; Belongs to the NiCoT transporter (TC 2.A.52) family.
       0.800
AEI07719.1
Hypothetical protein.
       0.800
AEI04879.1
Putative transmembrane protein.
 
  
 0.779
ubiA
4-hydroxybenzoate-octaprenyl transferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.
    
 0.750
ctaB
Protoheme IX farnesyltransferase CtaB; Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
   
 
 0.719
ctaA
Heme A synthase CtaA; Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group; Belongs to the COX15/CtaA family. Type 2 subfamily.
  
 
 0.718
bfr
Bacterioferritin; Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex; Belongs to the bacterioferritin family.
     
 0.715
hemF
coproporphyrinogen-III oxidase, aerobic; Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen- IX.
 
   
 0.698
Your Current Organism:
Oligotropha carboxidovorans
NCBI taxonomy Id: 504832
Other names: O. carboxidovorans OM5, Oligotropha carboxidovorans OM5, Oligotropha carboxidovorans str. OM5, Oligotropha carboxidovorans strain OM5
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