| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AEI07324.1 | glyA | OCA5_c26290 | OCA5_c21580 | Serine/threonine dehydratase. | Serine hydroxymethyltransferase GlyA; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.911 |
| AEI07324.1 | pabB | OCA5_c26290 | OCA5_c27510 | Serine/threonine dehydratase. | Para-aminobenzoate synthase PabB. | 0.469 |
| AEI07324.1 | serB | OCA5_c26290 | OCA5_c26900 | Serine/threonine dehydratase. | Phosphoserine phosphatase SerB. | 0.905 |
| AEI07324.1 | sgaA1 | OCA5_c26290 | OCA5_c13760 | Serine/threonine dehydratase. | Serine--glyoxylate aminotransferase SgaA. | 0.905 |
| AEI07324.1 | trpA | OCA5_c26290 | OCA5_c00560 | Serine/threonine dehydratase. | Tryptophan synthase alpha chain TrpA; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.906 |
| AEI07324.1 | trpB | OCA5_c26290 | OCA5_c00570 | Serine/threonine dehydratase. | Tryptophan synthase beta chain TrpB; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.923 |
| AEI07324.1 | trpE(G) | OCA5_c26290 | OCA5_c10970 | Serine/threonine dehydratase. | Anthranilate synthase. | 0.469 |
| glyA | AEI07324.1 | OCA5_c21580 | OCA5_c26290 | Serine hydroxymethyltransferase GlyA; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Serine/threonine dehydratase. | 0.911 |
| glyA | pabB | OCA5_c21580 | OCA5_c27510 | Serine hydroxymethyltransferase GlyA; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Para-aminobenzoate synthase PabB. | 0.585 |
| glyA | serB | OCA5_c21580 | OCA5_c26900 | Serine hydroxymethyltransferase GlyA; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Phosphoserine phosphatase SerB. | 0.942 |
| glyA | sgaA1 | OCA5_c21580 | OCA5_c13760 | Serine hydroxymethyltransferase GlyA; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Serine--glyoxylate aminotransferase SgaA. | 0.919 |
| glyA | trpA | OCA5_c21580 | OCA5_c00560 | Serine hydroxymethyltransferase GlyA; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Tryptophan synthase alpha chain TrpA; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.932 |
| glyA | trpB | OCA5_c21580 | OCA5_c00570 | Serine hydroxymethyltransferase GlyA; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Tryptophan synthase beta chain TrpB; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.927 |
| glyA | trpD | OCA5_c21580 | OCA5_c17300 | Serine hydroxymethyltransferase GlyA; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Anthranilate phosphoribosyltransferase TrpD; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). | 0.413 |
| glyA | trpE(G) | OCA5_c21580 | OCA5_c10970 | Serine hydroxymethyltransferase GlyA; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Anthranilate synthase. | 0.585 |
| pabB | AEI07324.1 | OCA5_c27510 | OCA5_c26290 | Para-aminobenzoate synthase PabB. | Serine/threonine dehydratase. | 0.469 |
| pabB | glyA | OCA5_c27510 | OCA5_c21580 | Para-aminobenzoate synthase PabB. | Serine hydroxymethyltransferase GlyA; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.585 |
| pabB | trpA | OCA5_c27510 | OCA5_c00560 | Para-aminobenzoate synthase PabB. | Tryptophan synthase alpha chain TrpA; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.993 |
| pabB | trpB | OCA5_c27510 | OCA5_c00570 | Para-aminobenzoate synthase PabB. | Tryptophan synthase beta chain TrpB; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.992 |
| pabB | trpC | OCA5_c27510 | OCA5_c17290 | Para-aminobenzoate synthase PabB. | Indole-3-glycerol phosphate synthase TrpC; Belongs to the TrpC family. | 0.998 |
