STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MCRY_09695Serine dehydratase; Bacteria available from JCM 15447. Source DNA available from JCM 15447; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the iron-sulfur dependent L-serine dehydratase family. (457 aa)    
Predicted Functional Partners:
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
  
 
 0.957
MCRY_01785
Phosphoserine phosphatase; Bacteria available from JCM 15447. Source DNA available from JCM 15447; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.893
MCRY_10730
Serine acetyltransferase; Bacteria available from JCM 15447. Source DNA available from JCM 15447; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.887
MCRY_04005
Homoserine dehydrogenase; Bacteria available from JCM 15447. Source DNA available from JCM 15447; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.883
metAA
Homoserine O-succinyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine; Belongs to the MetA family.
     
 0.878
trpA
Tryptophan synthase subunit alpha; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.
   
 
  0.867
gcvP
Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.
 
  
 0.829
MCRY_15515
Glutamine amidotransferase; Bacteria available from JCM 15447. Source DNA available from JCM 15447; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
  0.827
MCRY_09700
Hypothetical protein; Bacteria available from JCM 15447. Source DNA available from JCM 15447; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.784
metZ
O-succinylhomoserine sulfhydrylase; Catalyzes the formation of L-homocysteine from O-succinyl-L- homoserine (OSHS) and hydrogen sulfide.
     
 0.762
Your Current Organism:
Marivita cryptomonadis
NCBI taxonomy Id: 505252
Other names: JCM 15447, KCCM 90070, M. cryptomonadis, Marivita cryptomonadis Hwang et al. 2009, Rhodobacteraceae bacterium CL-SK44, strain CL-SK44
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