STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MCRY_11300Methylenetetrahydrofolate reductase; Bacteria available from JCM 15447. Source DNA available from JCM 15447; Derived by automated computational analysis using gene prediction method: Protein Homology. (308 aa)    
Predicted Functional Partners:
MCRY_11310
Methyltetrahydrofolate:corrinoid methyltransferase; Bacteria available from JCM 15447. Source DNA available from JCM 15447; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.993
MCRY_17085
Methionine synthase I; Bacteria available from JCM 15447. Source DNA available from JCM 15447; catalyzes the formation of methionine from L-homocysteine and S-adenosyl-L-methionine; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.969
MCRY_11295
Hypothetical protein; Bacteria available from JCM 15447. Source DNA available from JCM 15447; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
    0.951
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
  
 
 0.919
rpsF
30S ribosomal protein S6; Binds together with S18 to 16S ribosomal RNA.
  
 
 0.919
metF
5,10-methylenetetrahydrofolate reductase; Bacteria available from JCM 15447. Source DNA available from JCM 15447; MTHFR; catalyzes NADH-linked reduction of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate using FAD as a cofactor; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the methylenetetrahydrofolate reductase family.
     
 0.916
MCRY_09120
Enterotoxin; Bacteria available from JCM 15447. Source DNA available from JCM 15447; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.911
folD
Methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate.
    
 0.892
thyX
FAD-dependent thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.
     
 0.874
gcvT
Glycine cleavage system protein T; Bacteria available from JCM 15447. Source DNA available from JCM 15447; catalyzes the transfer of a methylene carbon from the methylamine-loaded GcvH protein to tetrahydrofolate, causing the release of ammonia and the generation of reduced GcvH protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
  0.871
Your Current Organism:
Marivita cryptomonadis
NCBI taxonomy Id: 505252
Other names: JCM 15447, KCCM 90070, M. cryptomonadis, Marivita cryptomonadis Hwang et al. 2009, Rhodobacteraceae bacterium CL-SK44, strain CL-SK44
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