node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
OBX07124.1 | OBX07126.1 | QV08_07935 | QV08_07945 | Global regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. | Lipoprotein NlpI-like protein; May be involved in cell division. | 0.582 |
OBX07124.1 | OBX07135.1 | QV08_07935 | QV08_07990 | Global regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. | Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. | 0.594 |
OBX07124.1 | OBX07686.1 | QV08_07935 | QV08_06775 | Global regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. | Catalyzes the reduction of 2 glutathione to glutathione disulfide; maintains high levels of reduced glutathione in the cytosol; involved in redox regulation and oxidative defense; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.479 |
OBX07124.1 | OBX08703.1 | QV08_07935 | QV08_03840 | Global regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. | Iron transporter; Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes. | 0.523 |
OBX07124.1 | OBX08773.1 | QV08_07935 | QV08_03475 | Global regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. | E3 component of pyruvate and 2-oxoglutarate dehydrogenase complex; catalyzes the oxidation of dihydrolipoamide to lipoamide; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.562 |
OBX07124.1 | deaD | QV08_07935 | QV08_07940 | Global regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. | DEAD/DEAH box helicase; DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation. | 0.650 |
OBX07124.1 | erpA | QV08_07935 | QV08_06740 | Global regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. | Iron-sulfur cluster insertion protein ErpA; Required for insertion of 4Fe-4S clusters for at least IspG. | 0.659 |
OBX07124.1 | glyA | QV08_07935 | QV08_11070 | Global regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.612 |
OBX07124.1 | iscA | QV08_07935 | QV08_04690 | Global regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. | Iron-sulfur cluster assembly protein; Is able to transfer iron-sulfur clusters to apo-ferredoxin. Multiple cycles of [2Fe2S] cluster formation and transfer are observed, suggesting that IscA acts catalytically. Recruits intracellular free iron so as to provide iron for the assembly of transient iron-sulfur cluster in IscU in the presence of IscS, L-cysteine and the thioredoxin reductase system; Belongs to the HesB/IscA family. | 0.572 |
OBX07124.1 | nfuA | QV08_07935 | QV08_09900 | Global regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. | Amino acid ABC transporter substrate-binding protein; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins. | 0.693 |
OBX07126.1 | OBX07124.1 | QV08_07945 | QV08_07935 | Lipoprotein NlpI-like protein; May be involved in cell division. | Global regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.582 |
OBX07126.1 | deaD | QV08_07945 | QV08_07940 | Lipoprotein NlpI-like protein; May be involved in cell division. | DEAD/DEAH box helicase; DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation. | 0.651 |
OBX07135.1 | OBX07124.1 | QV08_07990 | QV08_07935 | Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. | Global regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.594 |
OBX07135.1 | OBX07686.1 | QV08_07990 | QV08_06775 | Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. | Catalyzes the reduction of 2 glutathione to glutathione disulfide; maintains high levels of reduced glutathione in the cytosol; involved in redox regulation and oxidative defense; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.481 |
OBX07135.1 | OBX08773.1 | QV08_07990 | QV08_03475 | Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. | E3 component of pyruvate and 2-oxoglutarate dehydrogenase complex; catalyzes the oxidation of dihydrolipoamide to lipoamide; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.563 |
OBX07135.1 | glyA | QV08_07990 | QV08_11070 | Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.735 |
OBX07686.1 | OBX07124.1 | QV08_06775 | QV08_07935 | Catalyzes the reduction of 2 glutathione to glutathione disulfide; maintains high levels of reduced glutathione in the cytosol; involved in redox regulation and oxidative defense; Derived by automated computational analysis using gene prediction method: Protein Homology. | Global regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.479 |
OBX07686.1 | OBX07135.1 | QV08_06775 | QV08_07990 | Catalyzes the reduction of 2 glutathione to glutathione disulfide; maintains high levels of reduced glutathione in the cytosol; involved in redox regulation and oxidative defense; Derived by automated computational analysis using gene prediction method: Protein Homology. | Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. | 0.481 |
OBX07686.1 | glyA | QV08_06775 | QV08_11070 | Catalyzes the reduction of 2 glutathione to glutathione disulfide; maintains high levels of reduced glutathione in the cytosol; involved in redox regulation and oxidative defense; Derived by automated computational analysis using gene prediction method: Protein Homology. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.606 |
OBX08703.1 | OBX07124.1 | QV08_03840 | QV08_07935 | Iron transporter; Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes. | Global regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.523 |