node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
GAU83361.1 | GAU83363.1 | BIWAKO_03285 | BIWAKO_03287 | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase. | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | 0.999 |
GAU83361.1 | GAU84966.1 | BIWAKO_03285 | BIWAKO_04908 | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase. | Anthranilate synthase amidotransferase component. | 0.740 |
GAU83361.1 | trpE | BIWAKO_03285 | BIWAKO_04911 | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase. | Anthranilate synthase aminase component; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high co [...] | 0.845 |
GAU83363.1 | GAU83361.1 | BIWAKO_03287 | BIWAKO_03285 | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase. | 0.999 |
GAU83363.1 | GAU84966.1 | BIWAKO_03287 | BIWAKO_04908 | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | Anthranilate synthase amidotransferase component. | 0.855 |
GAU83363.1 | trpE | BIWAKO_03287 | BIWAKO_04911 | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | Anthranilate synthase aminase component; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high co [...] | 0.902 |
GAU84966.1 | GAU83361.1 | BIWAKO_04908 | BIWAKO_03285 | Anthranilate synthase amidotransferase component. | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase. | 0.740 |
GAU84966.1 | GAU83363.1 | BIWAKO_04908 | BIWAKO_03287 | Anthranilate synthase amidotransferase component. | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | 0.855 |
GAU84966.1 | aroC | BIWAKO_04908 | BIWAKO_03291 | Anthranilate synthase amidotransferase component. | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | 0.918 |
GAU84966.1 | trpA | BIWAKO_04908 | BIWAKO_01801 | Anthranilate synthase amidotransferase component. | Tryptophan synthase alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.994 |
GAU84966.1 | trpB | BIWAKO_04908 | BIWAKO_01803 | Anthranilate synthase amidotransferase component. | Tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.995 |
GAU84966.1 | trpC | BIWAKO_04908 | BIWAKO_04906 | Anthranilate synthase amidotransferase component. | Indole-3-glycerol phosphate synthase; Belongs to the TrpC family. | 0.999 |
GAU84966.1 | trpD | BIWAKO_04908 | BIWAKO_04907 | Anthranilate synthase amidotransferase component. | Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). | 0.999 |
GAU84966.1 | trpE | BIWAKO_04908 | BIWAKO_04911 | Anthranilate synthase amidotransferase component. | Anthranilate synthase aminase component; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high co [...] | 0.999 |
GAU84966.1 | trpF | BIWAKO_04908 | BIWAKO_01804 | Anthranilate synthase amidotransferase component. | Phosphoribosylanthranilate isomerase; Belongs to the TrpF family. | 0.996 |
GAU84966.1 | trpF-2 | BIWAKO_04908 | BIWAKO_06585 | Anthranilate synthase amidotransferase component. | Phosphoribosylanthranilate isomerase; Belongs to the TrpF family. | 0.986 |
aroC | GAU84966.1 | BIWAKO_03291 | BIWAKO_04908 | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | Anthranilate synthase amidotransferase component. | 0.918 |
aroC | trpA | BIWAKO_03291 | BIWAKO_01801 | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | Tryptophan synthase alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.931 |
aroC | trpB | BIWAKO_03291 | BIWAKO_01803 | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | Tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.833 |
aroC | trpC | BIWAKO_03291 | BIWAKO_04906 | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | Indole-3-glycerol phosphate synthase; Belongs to the TrpC family. | 0.876 |