node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
KIN12139.1 | KIN12140.1 | SU60_03305 | SU60_03310 | Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | ABC transporter ATPase; Uup; in Escherichia coli this cytoplasmic protein was shown to contain ATPase activity; mutations in this gene affect RecA-independent excision of transposons and affects Mu bacteriophage growth; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.800 |
KIN12139.1 | KIN12141.1 | SU60_03305 | SU60_03315 | Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Glutaredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.800 |
KIN12139.1 | rlmL | SU60_03305 | SU60_03320 | Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 23S rRNA methyltransferase; Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA. Belongs to the methyltransferase superfamily. RlmKL family. | 0.760 |
KIN12140.1 | KIN12139.1 | SU60_03310 | SU60_03305 | ABC transporter ATPase; Uup; in Escherichia coli this cytoplasmic protein was shown to contain ATPase activity; mutations in this gene affect RecA-independent excision of transposons and affects Mu bacteriophage growth; Derived by automated computational analysis using gene prediction method: Protein Homology. | Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.800 |
KIN12140.1 | KIN12141.1 | SU60_03310 | SU60_03315 | ABC transporter ATPase; Uup; in Escherichia coli this cytoplasmic protein was shown to contain ATPase activity; mutations in this gene affect RecA-independent excision of transposons and affects Mu bacteriophage growth; Derived by automated computational analysis using gene prediction method: Protein Homology. | Glutaredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.801 |
KIN12140.1 | rlmL | SU60_03310 | SU60_03320 | ABC transporter ATPase; Uup; in Escherichia coli this cytoplasmic protein was shown to contain ATPase activity; mutations in this gene affect RecA-independent excision of transposons and affects Mu bacteriophage growth; Derived by automated computational analysis using gene prediction method: Protein Homology. | 23S rRNA methyltransferase; Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA. Belongs to the methyltransferase superfamily. RlmKL family. | 0.827 |
KIN12141.1 | KIN12139.1 | SU60_03315 | SU60_03305 | Glutaredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology. | Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.800 |
KIN12141.1 | KIN12140.1 | SU60_03315 | SU60_03310 | Glutaredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology. | ABC transporter ATPase; Uup; in Escherichia coli this cytoplasmic protein was shown to contain ATPase activity; mutations in this gene affect RecA-independent excision of transposons and affects Mu bacteriophage growth; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.801 |
KIN12141.1 | rlmL | SU60_03315 | SU60_03320 | Glutaredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology. | 23S rRNA methyltransferase; Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA. Belongs to the methyltransferase superfamily. RlmKL family. | 0.747 |
birA | rlmL | SU60_11085 | SU60_03320 | biotin--[acetyl-CoA-carboxylase] synthetase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon. | 23S rRNA methyltransferase; Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA. Belongs to the methyltransferase superfamily. RlmKL family. | 0.624 |
pnp | polA | SU60_14575 | SU60_12220 | Polynucleotide phosphorylase/polyadenylase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.545 |
pnp | pyrG | SU60_14575 | SU60_00575 | Polynucleotide phosphorylase/polyadenylase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. | CTP synthetase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. | 0.887 |
pnp | rlmL | SU60_14575 | SU60_03320 | Polynucleotide phosphorylase/polyadenylase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. | 23S rRNA methyltransferase; Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA. Belongs to the methyltransferase superfamily. RlmKL family. | 0.668 |
pnp | uppS | SU60_14575 | SU60_13810 | Polynucleotide phosphorylase/polyadenylase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. | UDP pyrophosphate synthase; Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di- trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide. | 0.757 |
polA | pnp | SU60_12220 | SU60_14575 | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | Polynucleotide phosphorylase/polyadenylase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. | 0.545 |
polA | pyrG | SU60_12220 | SU60_00575 | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | CTP synthetase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. | 0.449 |
polA | rlmL | SU60_12220 | SU60_03320 | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 23S rRNA methyltransferase; Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA. Belongs to the methyltransferase superfamily. RlmKL family. | 0.602 |
polA | thiI | SU60_12220 | SU60_09830 | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | tRNA s(4)U8 sulfurtransferase; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. | 0.467 |
polA | uppS | SU60_12220 | SU60_13810 | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | UDP pyrophosphate synthase; Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di- trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide. | 0.500 |
pyrG | pnp | SU60_00575 | SU60_14575 | CTP synthetase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. | Polynucleotide phosphorylase/polyadenylase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. | 0.887 |