Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
EDM43394.1Alkyl hydroperoxide reductase, F52a subunit; COG0492 Thioredoxin reductase. (333 aa)    
Predicted Functional Partners:
gcvP
Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.
     
 0.844
EDM44279.1
Molybdopterin oxidoreductase, iron-sulfur binding subunit; COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
     
  0.784
EDM42924.1
Ferredoxin-dependent glutamate synthase; COG2146 Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases.
    
  0.739
EDM43393.1
Putative transcription regulator; COG0735 Fe2+/Zn2+ uptake regulation proteins; Belongs to the Fur family.
 
     0.681
EDM44289.1
Thioredoxin C-2; COG0526 Thiol-disulfide isomerase and thioredoxins.
  
  0.628
EDM43688.1
Thioredoxin; COG0526 Thiol-disulfide isomerase and thioredoxins; Belongs to the thioredoxin family.
  
  0.628
EDM44031.1
Hypothetical protein; COG0526 Thiol-disulfide isomerase and thioredoxins.
  
  0.628
EDM45008.1
Antioxidant, AhpC/TSA family protein; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.
  
 
 0.574
EDM43119.1
Putative thioredoxin peroxidase; COG0450 Peroxiredoxin.
  
 
 0.574
EDM45645.1
COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2.
  
    0.501
Your Current Organism:
unidentified eubacterium SCB49
NCBI taxonomy Id: 50743
Other names: u. eubacterium SCB49
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