Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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fumCFumarate hydratase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (463 aa)    
Predicted Functional Partners:
sdhA
COG1053 Succinate dehydrogenase/fumarate reductase, flavoprotein subunit.
 
 0.974
EDM43846.1
COG0372 Citrate synthase; Belongs to the citrate synthase family.
   
 0.954
EDM44267.1
COG0281 Malic enzyme.
  
 
 0.948
mdh
Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family.
  
 0.947
EDM43171.1
Aconitate hydratase; COG1048 Aconitase A.
  
 0.941
EDM44339.1
COG0479 Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
  
 0.929
EDM44279.1
Molybdopterin oxidoreductase, iron-sulfur binding subunit; COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
     
 0.879
guaB
Putative inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
    
 0.847
EDM43089.1
Probable oxidoreductase; COG0277 FAD/FMN-containing dehydrogenases.
   
 
 0.838
argH
COG0165 Argininosuccinate lyase.
   
 
 0.817
Your Current Organism:
unidentified eubacterium SCB49
NCBI taxonomy Id: 50743
Other names: u. eubacterium SCB49
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