STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
EDM43247.1Hypothetical protein. (244 aa)    
Predicted Functional Partners:
EDM44244.1
NADH oxidase, putative; COG0446 Uncharacterized NAD(FAD)-dependent dehydrogenases.
  
     0.737
EDM43637.1
Hypothetical protein; COG0477 Permeases of the major facilitator superfamily.
 
     0.713
EDM44246.1
Glycosyl transferase, group 2 family protein; COG0463 Glycosyltransferases involved in cell wall biogenesis.
  
     0.686
EDM44245.1
Pyridine nucleotide-disulphide oxidoreductase domain protein; COG0348 Polyferredoxin.
  
     0.676
EDM44243.1
Hypothetical protein.
 
     0.607
EDM43212.1
COG1109 Phosphomannomutase.
     
  0.595
EDM43248.1
COG0739 Membrane proteins related to metalloendopeptidases.
       0.553
EDM44026.1
Hypothetical protein.
 
     0.538
EDM45134.1
Integral membrane protein; COG1988 Predicted membrane-bound metal-dependent hydrolases.
  
     0.531
smpB
SsrA-binding protein; Required for rescue of stalled ribosomes mediated by trans- translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to [...]
       0.494
Your Current Organism:
unidentified eubacterium SCB49
NCBI taxonomy Id: 50743
Other names: u. eubacterium SCB49
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.