| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EDM43258.1 | EDM43436.1 | SCB49_00847 | SCB49_00265 | COG2176 DNA polymerase III, alpha subunit (gram-positive type). | Excinuclease ABC subunit A; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. | 0.890 |
| EDM43258.1 | EDM43491.1 | SCB49_00847 | SCB49_00540 | COG2176 DNA polymerase III, alpha subunit (gram-positive type). | COG0210 Superfamily I DNA and RNA helicases. | 0.926 |
| EDM43258.1 | EDM43686.1 | SCB49_00847 | SCB49_08848 | COG2176 DNA polymerase III, alpha subunit (gram-positive type). | COG2176 DNA polymerase III, alpha subunit (gram-positive type). | 0.992 |
| EDM43258.1 | EDM43961.1 | SCB49_00847 | SCB49_10237 | COG2176 DNA polymerase III, alpha subunit (gram-positive type). | Hypothetical protein; COG1466 DNA polymerase III, delta subunit. | 0.906 |
| EDM43258.1 | EDM44043.1 | SCB49_00847 | SCB49_10647 | COG2176 DNA polymerase III, alpha subunit (gram-positive type). | Excinuclease ABC subunit A; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. | 0.891 |
| EDM43258.1 | ligA | SCB49_00847 | SCB49_00927 | COG2176 DNA polymerase III, alpha subunit (gram-positive type). | Putative DNA ligase; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA. | 0.890 |
| EDM43258.1 | ruvA | SCB49_00847 | SCB49_04535 | COG2176 DNA polymerase III, alpha subunit (gram-positive type). | Holliday junction DNA helicase; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. | 0.884 |
| EDM43258.1 | ruvB | SCB49_00847 | SCB49_04555 | COG2176 DNA polymerase III, alpha subunit (gram-positive type). | Holliday junction DNA helicase B; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. | 0.886 |
| EDM43258.1 | ruvC | SCB49_00847 | SCB49_03434 | COG2176 DNA polymerase III, alpha subunit (gram-positive type). | Holliday junction resolvase; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group. | 0.889 |
| EDM43258.1 | uvrB | SCB49_00847 | SCB49_14180 | COG2176 DNA polymerase III, alpha subunit (gram-positive type). | Excinuclease ABC subunit B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...] | 0.983 |
| EDM43436.1 | EDM43258.1 | SCB49_00265 | SCB49_00847 | Excinuclease ABC subunit A; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. | COG2176 DNA polymerase III, alpha subunit (gram-positive type). | 0.890 |
| EDM43436.1 | EDM43491.1 | SCB49_00265 | SCB49_00540 | Excinuclease ABC subunit A; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. | COG0210 Superfamily I DNA and RNA helicases. | 0.534 |
| EDM43436.1 | EDM43686.1 | SCB49_00265 | SCB49_08848 | Excinuclease ABC subunit A; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. | COG2176 DNA polymerase III, alpha subunit (gram-positive type). | 0.788 |
| EDM43436.1 | EDM44043.1 | SCB49_00265 | SCB49_10647 | Excinuclease ABC subunit A; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. | Excinuclease ABC subunit A; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. | 0.793 |
| EDM43436.1 | ruvA | SCB49_00265 | SCB49_04535 | Excinuclease ABC subunit A; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. | Holliday junction DNA helicase; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. | 0.817 |
| EDM43436.1 | ruvB | SCB49_00265 | SCB49_04555 | Excinuclease ABC subunit A; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. | Holliday junction DNA helicase B; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. | 0.816 |
| EDM43436.1 | ruvC | SCB49_00265 | SCB49_03434 | Excinuclease ABC subunit A; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. | Holliday junction resolvase; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group. | 0.813 |
| EDM43436.1 | uvrB | SCB49_00265 | SCB49_14180 | Excinuclease ABC subunit A; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. | Excinuclease ABC subunit B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...] | 0.997 |
| EDM43491.1 | EDM43258.1 | SCB49_00540 | SCB49_00847 | COG0210 Superfamily I DNA and RNA helicases. | COG2176 DNA polymerase III, alpha subunit (gram-positive type). | 0.926 |
| EDM43491.1 | EDM43436.1 | SCB49_00540 | SCB49_00265 | COG0210 Superfamily I DNA and RNA helicases. | Excinuclease ABC subunit A; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. | 0.534 |
