EDM43296.1 protein (unidentified eubacterium SCB49)

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EDM43296.1

Ribosomal large subunit pseudouridine synthase D; COG0564 Pseudouridylate synthases, 23S RNA-specific. (300 aa)

Predicted Functional Partners:

EDM43295.1

0.773

rplM

0.707

rplC

0.701

trmB

0.696

rplU

0.663

rplQ

0.662

rsfS

0.657

rplO

0.656

rplN

0.653

obg

0.651

Your Current Organism:

unidentified eubacterium SCB49

NCBI taxonomy Id: 50743
Other names: u. eubacterium SCB49

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
EDM43295.1	EDM43296.1	SCB49_01032	SCB49_01037	Hypothetical protein.	Ribosomal large subunit pseudouridine synthase D; COG0564 Pseudouridylate synthases, 23S RNA-specific.	0.773
EDM43296.1	EDM43295.1	SCB49_01037	SCB49_01032	Ribosomal large subunit pseudouridine synthase D; COG0564 Pseudouridylate synthases, 23S RNA-specific.	Hypothetical protein.	0.773
EDM43296.1	obg	SCB49_01037	SCB49_04145	Ribosomal large subunit pseudouridine synthase D; COG0564 Pseudouridylate synthases, 23S RNA-specific.	Putative Spo0B-related GTP-binding protein; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.	0.651
EDM43296.1	rplC	SCB49_01037	SCB49_09500	Ribosomal large subunit pseudouridine synthase D; COG0564 Pseudouridylate synthases, 23S RNA-specific.	50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family.	0.701
EDM43296.1	rplM	SCB49_01037	SCB49_04700	Ribosomal large subunit pseudouridine synthase D; COG0564 Pseudouridylate synthases, 23S RNA-specific.	50S ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.	0.707
EDM43296.1	rplN	SCB49_01037	SCB49_09550	Ribosomal large subunit pseudouridine synthase D; COG0564 Pseudouridylate synthases, 23S RNA-specific.	50S ribosomal protein L14; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family.	0.653
EDM43296.1	rplO	SCB49_01037	SCB49_09595	Ribosomal large subunit pseudouridine synthase D; COG0564 Pseudouridylate synthases, 23S RNA-specific.	50S ribosomal protein L15; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family.	0.656
EDM43296.1	rplQ	SCB49_01037	SCB49_09635	Ribosomal large subunit pseudouridine synthase D; COG0564 Pseudouridylate synthases, 23S RNA-specific.	COG0203 Ribosomal protein L17.	0.662
EDM43296.1	rplU	SCB49_01037	SCB49_07602	Ribosomal large subunit pseudouridine synthase D; COG0564 Pseudouridylate synthases, 23S RNA-specific.	Ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family.	0.663
EDM43296.1	rsfS	SCB49_01037	SCB49_03754	Ribosomal large subunit pseudouridine synthase D; COG0564 Pseudouridylate synthases, 23S RNA-specific.	Hypothetical protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.	0.657
EDM43296.1	trmB	SCB49_01037	SCB49_08783	Ribosomal large subunit pseudouridine synthase D; COG0564 Pseudouridylate synthases, 23S RNA-specific.	tRNA (guanine-N(7))-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.	0.696
obg	EDM43296.1	SCB49_04145	SCB49_01037	Putative Spo0B-related GTP-binding protein; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.	Ribosomal large subunit pseudouridine synthase D; COG0564 Pseudouridylate synthases, 23S RNA-specific.	0.651
obg	rplC	SCB49_04145	SCB49_09500	Putative Spo0B-related GTP-binding protein; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.	50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family.	0.795
obg	rplM	SCB49_04145	SCB49_04700	Putative Spo0B-related GTP-binding protein; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.	50S ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.	0.830
obg	rplN	SCB49_04145	SCB49_09550	Putative Spo0B-related GTP-binding protein; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.	50S ribosomal protein L14; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family.	0.792
obg	rplO	SCB49_04145	SCB49_09595	Putative Spo0B-related GTP-binding protein; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.	50S ribosomal protein L15; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family.	0.822
obg	rplQ	SCB49_04145	SCB49_09635	Putative Spo0B-related GTP-binding protein; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.	COG0203 Ribosomal protein L17.	0.826
obg	rplU	SCB49_04145	SCB49_07602	Putative Spo0B-related GTP-binding protein; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.	Ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family.	0.890
obg	rsfS	SCB49_04145	SCB49_03754	Putative Spo0B-related GTP-binding protein; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.	Hypothetical protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.	0.852
rplC	EDM43296.1	SCB49_09500	SCB49_01037	50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family.	Ribosomal large subunit pseudouridine synthase D; COG0564 Pseudouridylate synthases, 23S RNA-specific.	0.701