STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
EDM43308.1COG0720 6-pyruvoyl-tetrahydropterin synthase. (135 aa)    
Predicted Functional Partners:
queE
Hypothetical protein; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
 
 
 0.957
EDM45244.1
Conserved possible 6-pyruvoyl tetrahydrobiopterin synthase; COG0720 6-pyruvoyl-tetrahydropterin synthase.
  
  
  0.856
EDM43306.1
COG1482 Phosphomannose isomerase.
       0.809
EDM43309.1
Isopentenyl-diphosphate delta-isomerase; COG1443 Isopentenyldiphosphate isomerase.
       0.809
EDM43307.1
Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; COG1225 Peroxiredoxin.
       0.798
EDM44211.1
COG1785 Alkaline phosphatase; Belongs to the alkaline phosphatase family.
     
  0.788
EDM43305.1
Hypothetical protein; COG1193 Mismatch repair ATPase (MutS family).
       0.678
folE-2
COG0302 GTP cyclohydrolase I.
  
 
 0.610
folE
COG0302 GTP cyclohydrolase I.
  
 
 0.610
folE-3
COG0302 GTP cyclohydrolase I.
  
 
 0.610
Your Current Organism:
unidentified eubacterium SCB49
NCBI taxonomy Id: 50743
Other names: u. eubacterium SCB49
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.