EDM43353.1 protein (unidentified eubacterium SCB49)

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EDM43353.1

GTP-binding elongation factor family protein TypA/BipA; COG1217 Predicted membrane GTPase involved in stress response. (598 aa)

Predicted Functional Partners:

guaA

0.749

engA

0.718

rplA

0.673

rpsI

0.630

fusA

0.608

rpsJ

0.590

rpsB

0.585

rpoB

0.563

rpsD

0.558

tsf

0.543

Your Current Organism:

unidentified eubacterium SCB49

NCBI taxonomy Id: 50743
Other names: u. eubacterium SCB49

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
EDM43353.1	engA	SCB49_01322	SCB49_07882	GTP-binding elongation factor family protein TypA/BipA; COG1217 Predicted membrane GTPase involved in stress response.	GTP-binding protein EngA; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.	0.718
EDM43353.1	fusA	SCB49_01322	SCB49_09490	GTP-binding elongation factor family protein TypA/BipA; COG1217 Predicted membrane GTPase involved in stress response.	Elongation factor G; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.	0.608
EDM43353.1	guaA	SCB49_01322	SCB49_00510	GTP-binding elongation factor family protein TypA/BipA; COG1217 Predicted membrane GTPase involved in stress response.	Bifunctional GMP synthase/glutamine amidotransferase protein; Catalyzes the synthesis of GMP from XMP.	0.749
EDM43353.1	rplA	SCB49_01322	SCB49_01162	GTP-binding elongation factor family protein TypA/BipA; COG1217 Predicted membrane GTPase involved in stress response.	50S ribosomal protein L1; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.	0.673
EDM43353.1	rpoB	SCB49_01322	SCB49_01147	GTP-binding elongation factor family protein TypA/BipA; COG1217 Predicted membrane GTPase involved in stress response.	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.563
EDM43353.1	rpsB	SCB49_01322	SCB49_04710	GTP-binding elongation factor family protein TypA/BipA; COG1217 Predicted membrane GTPase involved in stress response.	COG0052 Ribosomal protein S2; Belongs to the universal ribosomal protein uS2 family.	0.585
EDM43353.1	rpsD	SCB49_01322	SCB49_09625	GTP-binding elongation factor family protein TypA/BipA; COG1217 Predicted membrane GTPase involved in stress response.	30S ribosomal protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.	0.558
EDM43353.1	rpsI	SCB49_01322	SCB49_04705	GTP-binding elongation factor family protein TypA/BipA; COG1217 Predicted membrane GTPase involved in stress response.	COG0103 Ribosomal protein S9; Belongs to the universal ribosomal protein uS9 family.	0.630
EDM43353.1	rpsJ	SCB49_01322	SCB49_09495	GTP-binding elongation factor family protein TypA/BipA; COG1217 Predicted membrane GTPase involved in stress response.	30S ribosomal protein S10; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family.	0.590
EDM43353.1	tsf	SCB49_01322	SCB49_04715	GTP-binding elongation factor family protein TypA/BipA; COG1217 Predicted membrane GTPase involved in stress response.	Elongation factor Ts; Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome. Belongs to the EF-Ts family.	0.543
engA	EDM43353.1	SCB49_07882	SCB49_01322	GTP-binding protein EngA; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.	GTP-binding elongation factor family protein TypA/BipA; COG1217 Predicted membrane GTPase involved in stress response.	0.718
engA	guaA	SCB49_07882	SCB49_00510	GTP-binding protein EngA; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.	Bifunctional GMP synthase/glutamine amidotransferase protein; Catalyzes the synthesis of GMP from XMP.	0.434
engA	rplA	SCB49_07882	SCB49_01162	GTP-binding protein EngA; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.	50S ribosomal protein L1; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.	0.716
fusA	EDM43353.1	SCB49_09490	SCB49_01322	Elongation factor G; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.	GTP-binding elongation factor family protein TypA/BipA; COG1217 Predicted membrane GTPase involved in stress response.	0.608
fusA	guaA	SCB49_09490	SCB49_00510	Elongation factor G; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.	Bifunctional GMP synthase/glutamine amidotransferase protein; Catalyzes the synthesis of GMP from XMP.	0.766
fusA	rplA	SCB49_09490	SCB49_01162	Elongation factor G; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.	50S ribosomal protein L1; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.	0.999
fusA	rpoB	SCB49_09490	SCB49_01147	Elongation factor G; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.946
fusA	rpsB	SCB49_09490	SCB49_04710	Elongation factor G; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.	COG0052 Ribosomal protein S2; Belongs to the universal ribosomal protein uS2 family.	0.999
fusA	rpsD	SCB49_09490	SCB49_09625	Elongation factor G; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.	30S ribosomal protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.	0.999
fusA	rpsI	SCB49_09490	SCB49_04705	Elongation factor G; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.	COG0103 Ribosomal protein S9; Belongs to the universal ribosomal protein uS9 family.	0.998