STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
EDM43367.1Probable transcriptional regulator, MerR family protein; COG0789 Predicted transcriptional regulators. (300 aa)    
Predicted Functional Partners:
EDM43369.1
COG1562 Phytoene/squalene synthetase.
 
     0.895
EDM43368.1
COG1233 Phytoene dehydrogenase and related proteins.
 
   
 0.891
EDM43370.1
Beta-carotene hydroxylase.
 
     0.861
EDM44267.1
COG0281 Malic enzyme.
    
 0.845
icmF
methylmalonyl-CoA mutase; Catalyzes the reversible interconversion of isobutyryl-CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly.
 
  
 0.839
EDM43686.1
COG2176 DNA polymerase III, alpha subunit (gram-positive type).
    
  0.815
ribB
Bifunctional protein: GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family.
     
  0.815
EDM44743.1
COG1884 Methylmalonyl-CoA mutase, N-terminal domain/subunit.
     
 0.773
EDM43258.1
COG2176 DNA polymerase III, alpha subunit (gram-positive type).
     
  0.769
EDM42916.1
COG0847 DNA polymerase III, epsilon subunit and related 3'-5' exonucleases.
     
  0.769
Your Current Organism:
unidentified eubacterium SCB49
NCBI taxonomy Id: 50743
Other names: u. eubacterium SCB49
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.