close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EDM44866.1Response regulatory protein, sigma 54 related; COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains. (387 aa)    
Predicted Functional Partners:
EDM45221.1
COG0642 Signal transduction histidine kinase.
 0.853
EDM45446.1
COG0642 Signal transduction histidine kinase.
 0.842
EDM45613.1
RNA polymerase, sigma-54 factor; COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog.
 
  
 0.838
EDM45534.1
Hybrid sensory kinase; COG0642 Signal transduction histidine kinase.
 0.799
EDM45173.1
Sensor histidine kinase; COG2202 FOG: PAS/PAC domain.
  
 0.786
EDM43866.1
Two-component system sensor histidine kinase; COG0642 Signal transduction histidine kinase.
 
 0.776
EDM44867.1
Hypothetical protein; COG0086 DNA-directed RNA polymerase, beta' subunit/160 kD subunit.
       0.774
EDM44865.1
Hypothetical protein.
       0.773
EDM44338.1
Histidine kinase; COG0642 Signal transduction histidine kinase.
0.765
EDM42881.1
Sensor histidine kinase/GAF domain hybrid protein; COG2203 FOG: GAF domain.
   
 0.703
Your Current Organism:
unidentified eubacterium SCB49
NCBI taxonomy Id: 50743
Other names: u. eubacterium SCB49
Server load: low (32%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.