STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
EDM44915.1Histidine kinase; COG0642 Signal transduction histidine kinase. (359 aa)    
Predicted Functional Partners:
EDM44914.1
Two component, sigma54 specific, transcriptional regulator, Fis family protein; COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains.
 
 
  0.946
EDM44127.1
COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.
 
  0.904
EDM43669.1
COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.
 
  0.885
EDM43604.1
(pyruvate) Oxoisovalerate Dehydrogenase Alpha and Beta Fusion; COG1071 Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit.
    
  0.864
EDM43022.1
Transketolase; COG1071 Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit.
    
  0.864
EDM43107.1
2-oxoisovalerate dehydrogenase, E1 component, alpha and beta fusion; COG1071 Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit.
    
  0.864
EDM45173.1
Sensor histidine kinase; COG2202 FOG: PAS/PAC domain.
  
0.812
EDM44910.1
COG0782 Transcription elongation factor.
 
     0.811
EDM43261.1
Two-component system, transcriptional regulatory protein; COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.
  
  0.727
ribB
Bifunctional protein: GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family.
     
  0.726
Your Current Organism:
unidentified eubacterium SCB49
NCBI taxonomy Id: 50743
Other names: u. eubacterium SCB49
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