| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EDM43472.1 | EDM43937.1 | SCB49_00445 | SCB49_10117 | COG0652 Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family. | Heat shock protein 90; COG0326 Molecular chaperone, HSP90 family. | 0.999 |
| EDM43472.1 | EDM44691.1 | SCB49_00445 | SCB49_14005 | COG0652 Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family. | COG0652 Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family. | 0.892 |
| EDM43472.1 | EDM44932.1 | SCB49_00445 | SCB49_02389 | COG0652 Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family. | Heat shock protein Hsp70; COG0443 Molecular chaperone. | 0.947 |
| EDM43472.1 | EDM44935.1 | SCB49_00445 | SCB49_02404 | COG0652 Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family. | Holliday junction DNA helicase; COG0515 Serine/threonine protein kinase; Belongs to the AAA ATPase family. | 0.462 |
| EDM43472.1 | dnaJ | SCB49_00445 | SCB49_02084 | COG0652 Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family. | Molecular chaperone, heat shock protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interaction [...] | 0.846 |
| EDM43937.1 | EDM43472.1 | SCB49_10117 | SCB49_00445 | Heat shock protein 90; COG0326 Molecular chaperone, HSP90 family. | COG0652 Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family. | 0.999 |
| EDM43937.1 | EDM44000.1 | SCB49_10117 | SCB49_10432 | Heat shock protein 90; COG0326 Molecular chaperone, HSP90 family. | Hypothetical protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dep [...] | 0.695 |
| EDM43937.1 | EDM44115.1 | SCB49_10117 | SCB49_11007 | Heat shock protein 90; COG0326 Molecular chaperone, HSP90 family. | ATP-dependent Clp protease, ATP-binding subunit; COG0542 ATPases with chaperone activity, ATP-binding subunit; Belongs to the ClpA/ClpB family. | 0.729 |
| EDM43937.1 | EDM44691.1 | SCB49_10117 | SCB49_14005 | Heat shock protein 90; COG0326 Molecular chaperone, HSP90 family. | COG0652 Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family. | 0.999 |
| EDM43937.1 | EDM44932.1 | SCB49_10117 | SCB49_02389 | Heat shock protein 90; COG0326 Molecular chaperone, HSP90 family. | Heat shock protein Hsp70; COG0443 Molecular chaperone. | 0.967 |
| EDM43937.1 | EDM44935.1 | SCB49_10117 | SCB49_02404 | Heat shock protein 90; COG0326 Molecular chaperone, HSP90 family. | Holliday junction DNA helicase; COG0515 Serine/threonine protein kinase; Belongs to the AAA ATPase family. | 0.798 |
| EDM43937.1 | clpB | SCB49_10117 | SCB49_00777 | Heat shock protein 90; COG0326 Molecular chaperone, HSP90 family. | Putative heat shock ClpB protein; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | 0.715 |
| EDM43937.1 | dnaJ | SCB49_10117 | SCB49_02084 | Heat shock protein 90; COG0326 Molecular chaperone, HSP90 family. | Molecular chaperone, heat shock protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interaction [...] | 0.934 |
| EDM43937.1 | grpE | SCB49_10117 | SCB49_02089 | Heat shock protein 90; COG0326 Molecular chaperone, HSP90 family. | Molecular chaperone, heat shock protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Severa [...] | 0.695 |
| EDM44000.1 | EDM43937.1 | SCB49_10432 | SCB49_10117 | Hypothetical protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dep [...] | Heat shock protein 90; COG0326 Molecular chaperone, HSP90 family. | 0.695 |
| EDM44000.1 | EDM44115.1 | SCB49_10432 | SCB49_11007 | Hypothetical protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dep [...] | ATP-dependent Clp protease, ATP-binding subunit; COG0542 ATPases with chaperone activity, ATP-binding subunit; Belongs to the ClpA/ClpB family. | 0.692 |
| EDM44000.1 | EDM44932.1 | SCB49_10432 | SCB49_02389 | Hypothetical protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dep [...] | Heat shock protein Hsp70; COG0443 Molecular chaperone. | 0.876 |
| EDM44000.1 | clpB | SCB49_10432 | SCB49_00777 | Hypothetical protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dep [...] | Putative heat shock ClpB protein; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | 0.692 |
| EDM44000.1 | dnaJ | SCB49_10432 | SCB49_02084 | Hypothetical protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dep [...] | Molecular chaperone, heat shock protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interaction [...] | 0.734 |
| EDM44115.1 | EDM43937.1 | SCB49_11007 | SCB49_10117 | ATP-dependent Clp protease, ATP-binding subunit; COG0542 ATPases with chaperone activity, ATP-binding subunit; Belongs to the ClpA/ClpB family. | Heat shock protein 90; COG0326 Molecular chaperone, HSP90 family. | 0.729 |
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