STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
EDM44953.1Type I restriction-modification system specificity determinant protein; COG0732 Restriction endonuclease S subunits. (415 aa)    
Predicted Functional Partners:
EDM44952.1
Hypothetical protein; COG0286 Type I restriction-modification system methyltransferase subunit.
 
 0.996
EDM44951.1
COG0610 Type I site-specific restriction-modification system, R (restriction) subunit and related helicases.
 
  
 0.978
EDM42831.1
COG0286 Type I restriction-modification system methyltransferase subunit.
 
 0.955
EDM44694.1
COG1002 Type II restriction enzyme, methylase subunits.
  
 0.932
EDM43960.1
Hypothetical protein.
  
 0.863
EDM44954.1
Hypothetical protein.
       0.773
atpF
ATP synthase, subunit B (H(+)-transporting two-sector ATPase); Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0); Belongs to the ATPase B chain family.
    
 0.753
EDM44962.1
COG4268 McrBC 5-methylcytosine restriction system component.
  
 
 0.750
EDM44961.1
5-Methylcytosine-specific restriction enzyme B; COG1196 Chromosome segregation ATPases.
  
 
 0.714
ruvB
Holliday junction DNA helicase B; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.
     
  0.687
Your Current Organism:
unidentified eubacterium SCB49
NCBI taxonomy Id: 50743
Other names: u. eubacterium SCB49
Server load: low (18%) [HD]