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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EDM44982.1Transcriptional regulator, sigma-54-related protein; COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains. (424 aa)    
Predicted Functional Partners:
EDM45221.1
COG0642 Signal transduction histidine kinase.
  
 0.993
EDM45173.1
Sensor histidine kinase; COG2202 FOG: PAS/PAC domain.
  
 0.990
EDM42881.1
Sensor histidine kinase/GAF domain hybrid protein; COG2203 FOG: GAF domain.
   
 0.988
ribB
Bifunctional protein: GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family.
    
  0.979
EDM44338.1
Histidine kinase; COG0642 Signal transduction histidine kinase.
  
 0.973
EDM45534.1
Hybrid sensory kinase; COG0642 Signal transduction histidine kinase.
 
 0.973
EDM43866.1
Two-component system sensor histidine kinase; COG0642 Signal transduction histidine kinase.
  
 0.973
EDM44128.1
Periplasmic sensor signal transduction histidine kinase; COG0591 Na+/proline symporter.
   
 0.962
EDM45613.1
RNA polymerase, sigma-54 factor; COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog.
 
  
 0.948
EDM43316.1
Hypothetical protein; COG2183 Transcriptional accessory protein.
   
 0.815
Your Current Organism:
unidentified eubacterium SCB49
NCBI taxonomy Id: 50743
Other names: u. eubacterium SCB49
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