| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EDM43467.1 | EDM45006.1 | SCB49_00420 | SCB49_02759 | Metallo-beta-lactamase superfamily protein; COG0491 Zn-dependent hydrolases, including glyoxylases. | Rhodanese-like protein; COG0491 Zn-dependent hydrolases, including glyoxylases. | 0.865 |
| EDM43467.1 | groL | SCB49_00420 | SCB49_02674 | Metallo-beta-lactamase superfamily protein; COG0491 Zn-dependent hydrolases, including glyoxylases. | Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.443 |
| EDM43467.1 | groS | SCB49_00420 | SCB49_02664 | Metallo-beta-lactamase superfamily protein; COG0491 Zn-dependent hydrolases, including glyoxylases. | Co-chaperonin GroES; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter. | 0.770 |
| EDM43937.1 | EDM44000.1 | SCB49_10117 | SCB49_10432 | Heat shock protein 90; COG0326 Molecular chaperone, HSP90 family. | Hypothetical protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dep [...] | 0.625 |
| EDM43937.1 | EDM44004.1 | SCB49_10117 | SCB49_10452 | Heat shock protein 90; COG0326 Molecular chaperone, HSP90 family. | Heat shock protein Hsp70; COG0443 Molecular chaperone; Belongs to the heat shock protein 70 family. | 0.947 |
| EDM43937.1 | EDM44932.1 | SCB49_10117 | SCB49_02389 | Heat shock protein 90; COG0326 Molecular chaperone, HSP90 family. | Heat shock protein Hsp70; COG0443 Molecular chaperone. | 0.960 |
| EDM43937.1 | EDM44934.1 | SCB49_10117 | SCB49_02399 | Heat shock protein 90; COG0326 Molecular chaperone, HSP90 family. | COG0443 Molecular chaperone; Belongs to the heat shock protein 70 family. | 0.947 |
| EDM43937.1 | dnaK | SCB49_10117 | SCB49_14405 | Heat shock protein 90; COG0326 Molecular chaperone, HSP90 family. | Molecular chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.960 |
| EDM43937.1 | groL | SCB49_10117 | SCB49_02674 | Heat shock protein 90; COG0326 Molecular chaperone, HSP90 family. | Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.984 |
| EDM43937.1 | groS | SCB49_10117 | SCB49_02664 | Heat shock protein 90; COG0326 Molecular chaperone, HSP90 family. | Co-chaperonin GroES; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter. | 0.849 |
| EDM43937.1 | grpE | SCB49_10117 | SCB49_02089 | Heat shock protein 90; COG0326 Molecular chaperone, HSP90 family. | Molecular chaperone, heat shock protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Severa [...] | 0.720 |
| EDM44000.1 | EDM43937.1 | SCB49_10432 | SCB49_10117 | Hypothetical protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dep [...] | Heat shock protein 90; COG0326 Molecular chaperone, HSP90 family. | 0.625 |
| EDM44000.1 | EDM44004.1 | SCB49_10432 | SCB49_10452 | Hypothetical protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dep [...] | Heat shock protein Hsp70; COG0443 Molecular chaperone; Belongs to the heat shock protein 70 family. | 0.980 |
| EDM44000.1 | EDM44932.1 | SCB49_10432 | SCB49_02389 | Hypothetical protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dep [...] | Heat shock protein Hsp70; COG0443 Molecular chaperone. | 0.922 |
| EDM44000.1 | EDM44934.1 | SCB49_10432 | SCB49_02399 | Hypothetical protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dep [...] | COG0443 Molecular chaperone; Belongs to the heat shock protein 70 family. | 0.922 |
| EDM44000.1 | dnaK | SCB49_10432 | SCB49_14405 | Hypothetical protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dep [...] | Molecular chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.922 |
| EDM44000.1 | groL | SCB49_10432 | SCB49_02674 | Hypothetical protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dep [...] | Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.912 |
| EDM44000.1 | groS | SCB49_10432 | SCB49_02664 | Hypothetical protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dep [...] | Co-chaperonin GroES; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter. | 0.811 |
| EDM44004.1 | EDM43937.1 | SCB49_10452 | SCB49_10117 | Heat shock protein Hsp70; COG0443 Molecular chaperone; Belongs to the heat shock protein 70 family. | Heat shock protein 90; COG0326 Molecular chaperone, HSP90 family. | 0.947 |
| EDM44004.1 | EDM44000.1 | SCB49_10452 | SCB49_10432 | Heat shock protein Hsp70; COG0443 Molecular chaperone; Belongs to the heat shock protein 70 family. | Hypothetical protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dep [...] | 0.980 |
