STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
EDM45028.1COG1956 GAF domain-containing protein. (151 aa)    
Predicted Functional Partners:
metK
Methionine adenosyltransferase (AdoMet synthetase); Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
     
  0.788
EDM45737.1
COG2873 O-acetylhomoserine sulfhydrylase.
     
  0.788
EDM45741.1
Methionine synthase I, homocysteine S-methyltransferase; COG0646 Methionine synthase I (cobalamin-dependent), methyltransferase domain.
     
  0.788
EDM45742.1
Methionine synthase I; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
     
  0.788
EDM43375.1
COG0599 Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit.
 
     0.786
EDM45027.1
COG4083 Predicted membrane protein.
       0.578
EDM44391.1
Cys/Met metabolism PLP-dependent enzyme superfamily protein; COG0626 Cystathionine beta-lyases/cystathionine gamma-synthases.
     
  0.428
EDM44020.1
COG0626 Cystathionine beta-lyases/cystathionine gamma-synthases.
     
  0.428
EDM43122.1
Probable Methionine gamma-lyase; COG0626 Cystathionine beta-lyases/cystathionine gamma-synthases.
     
  0.428
EDM45743.1
COG0685 5,10-methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family.
     
  0.409
Your Current Organism:
unidentified eubacterium SCB49
NCBI taxonomy Id: 50743
Other names: u. eubacterium SCB49
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