STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EDM45109.1COG1321 Mn-dependent transcriptional regulator. (218 aa)    
Predicted Functional Partners:
EDM45459.1
Hypothetical protein; COG1108 ABC-type Mn2+/Zn2+ transport systems, permease components.
 
 
 0.870
EDM45457.1
Zinc ABC transporter, ATP-binding protein; COG1121 ABC-type Mn/Zn transport systems, ATPase component.
  
 
 0.662
EDM45456.1
Zinc ABC transporter, periplasmic zinc-binding protein; COG0803 ABC-type metal ion transport system, periplasmic component/surface adhesin; Belongs to the bacterial solute-binding protein 9 family.
  
 
 0.651
thyA
Thymidylate synthetase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
    
  0.569
EDM45110.1
COG4771 Outer membrane receptor for ferrienterochelin and colicins.
       0.550
EDM45111.1
Hypothetical protein; COG0526 Thiol-disulfide isomerase and thioredoxins.
       0.538
EDM45458.1
Hypothetical protein; COG1108 ABC-type Mn2+/Zn2+ transport systems, permease components.
 
 
 0.432
Your Current Organism:
unidentified eubacterium SCB49
NCBI taxonomy Id: 50743
Other names: u. eubacterium SCB49
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.