STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EDM45189.1COG0294 Dihydropteroate synthase and related enzymes. (259 aa)    
Predicted Functional Partners:
EDM45707.1
Deoxyguanosine kinase/deoxyadenosine kinase subunit; COG0801 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase.
 
 
 0.991
EDM45061.1
COG0285 Folylpolyglutamate synthase.
 
 0.989
EDM45325.1
Putative dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin.
 
 
 0.978
folE
COG0302 GTP cyclohydrolase I.
 
 0.933
folE-2
COG0302 GTP cyclohydrolase I.
 
 
 0.917
folE-3
COG0302 GTP cyclohydrolase I.
 
 
 0.915
EDM43125.1
COG0147 Anthranilate/para-aminobenzoate synthases component I.
 
 
 0.777
EDM43893.1
COG0147 Anthranilate/para-aminobenzoate synthases component I.
 
 
 0.745
EDM43517.1
4-amino-4-deoxychorismate lyase, putative; COG0115 Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase.
 
 
 0.739
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
    
 0.730
Your Current Organism:
unidentified eubacterium SCB49
NCBI taxonomy Id: 50743
Other names: u. eubacterium SCB49
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.