STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
EDM44175.1Putative ADP-ribose pyrophosphatase protein; COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes. (186 aa)    
Predicted Functional Partners:
ribB
Bifunctional protein: GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family.
   
 0.873
nnrD
Hypothetical protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epi [...]
  
 0.855
EDM45560.1
Ribose-phosphate pyrophosphokinase; COG0462 Phosphoribosylpyrophosphate synthetase.
 
  
  0.822
EDM43212.1
COG1109 Phosphomannomutase.
    
  0.788
EDM45221.1
COG0642 Signal transduction histidine kinase.
    
  0.743
rnc
Putative ribonuclease III; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
    
 0.704
EDM43549.1
COG0513 Superfamily II DNA and RNA helicases.
    
  0.667
EDM43863.1
RNA helicase; COG0513 Superfamily II DNA and RNA helicases; Belongs to the DEAD box helicase family.
    
  0.667
EDM43194.1
ATP-dependent RNA helicase, DEAD/DEAH box family protein; COG0513 Superfamily II DNA and RNA helicases; Belongs to the DEAD box helicase family.
    
  0.667
EDM44467.1
COG0513 Superfamily II DNA and RNA helicases; Belongs to the DEAD box helicase family.
    
  0.667
Your Current Organism:
unidentified eubacterium SCB49
NCBI taxonomy Id: 50743
Other names: u. eubacterium SCB49
Server load: low (38%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.