STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
EDM44248.1Putative Hit-family protein; COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases. (129 aa)    
Predicted Functional Partners:
greA
Transcription elongation factor; Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.
       0.809
EDM44739.1
COG0572 Uridine kinase.
    
  0.664
cobB
COG0846 NAD-dependent protein deacetylases, SIR2 family; Belongs to the sirtuin family. Class III subfamily.
  
 
  0.607
EDM44250.1
Hypothetical protein.
       0.535
lysS
COG1190 Lysyl-tRNA synthetase (class II); Belongs to the class-II aminoacyl-tRNA synthetase family.
   
 0.534
EDM44414.1
COG0123 Deacetylases, including yeast histone deacetylase and acetoin utilization protein.
    
  0.515
EDM44251.1
Hypothetical protein.
       0.446
EDM43236.1
Sulfate adenylyltransferase, subunit 1; May be the GTPase, regulating ATP sulfurylase activity. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
     
  0.409
phhB
COG2154 Pterin-4a-carbinolamine dehydratase.
   
   0.406
Your Current Organism:
unidentified eubacterium SCB49
NCBI taxonomy Id: 50743
Other names: u. eubacterium SCB49
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.