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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EDM44248.1Putative Hit-family protein; COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases. (129 aa)    
Predicted Functional Partners:
greA
Transcription elongation factor; Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.
     
 0.800
rpoC
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
  0.633
EDM43270.1
Hypothetical protein; COG0419 ATPase involved in DNA repair.
   
 
  0.605
EDM44269.1
COG2124 Cytochrome P450.
     
 0.601
rpoB
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
  0.597
EDM45430.1
Hypothetical protein; COG1061 DNA or RNA helicases of superfamily II.
    
  0.583
EDM44527.1
Hypothetical protein; COG1061 DNA or RNA helicases of superfamily II.
    
  0.583
EDM44175.1
Putative ADP-ribose pyrophosphatase protein; COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes.
  
 0.556
EDM44055.1
Hydrolase, NUDIX family protein; COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes.
  
 0.556
EDM44250.1
Hypothetical protein.
       0.535
Your Current Organism:
unidentified eubacterium SCB49
NCBI taxonomy Id: 50743
Other names: u. eubacterium SCB49
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