Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
EDM44289.1Thioredoxin C-2; COG0526 Thiol-disulfide isomerase and thioredoxins. (98 aa)    
Predicted Functional Partners:
ribB
Bifunctional protein: GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family.
    
 0.805
EDM45577.1
COG0209 Ribonucleotide reductase, alpha subunit.
  
 0.803
groL
Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.
   
 
 0.723
EDM45576.1
COG0209 Ribonucleotide reductase, alpha subunit.
  
 
 0.682
EDM43444.1
COG0492 Thioredoxin reductase.
 
  0.670
EDM45200.1
Hypothetical protein; COG2866 Predicted carboxypeptidase.
    
   0.632
EDM43394.1
Alkyl hydroperoxide reductase, F52a subunit; COG0492 Thioredoxin reductase.
  
  0.628
EDM45159.1
Pyridine nucleotide-disulphide oxidoreductase, putative; COG0492 Thioredoxin reductase.
  
  0.628
EDM43678.1
COG0492 Thioredoxin reductase.
  
  0.628
fusA
Elongation factor G; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
    
 
 0.619
Your Current Organism:
unidentified eubacterium SCB49
NCBI taxonomy Id: 50743
Other names: u. eubacterium SCB49
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