STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
EDM44338.1Histidine kinase; COG0642 Signal transduction histidine kinase. (280 aa)    
Predicted Functional Partners:
EDM45173.1
Sensor histidine kinase; COG2202 FOG: PAS/PAC domain.
0.998
EDM42881.1
Sensor histidine kinase/GAF domain hybrid protein; COG2203 FOG: GAF domain.
 
0.992
EDM45174.1
Transcriptional regulator; COG0784 FOG: CheY-like receiver.
 0.987
ribB
Bifunctional protein: GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family.
    
 0.982
EDM44316.1
Two-component response regulator; COG0457 FOG: TPR repeat.
   
 0.980
EDM44982.1
Transcriptional regulator, sigma-54-related protein; COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains.
  
 0.968
EDM44077.1
Sensor histidine kinase/GAF domain hybrid protein; COG2203 FOG: GAF domain.
 
0.961
EDM45221.1
COG0642 Signal transduction histidine kinase.
   
 0.958
EDM43948.1
Hypothetical protein.
  
 0.953
EDM44127.1
COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.
 
 0.941
Your Current Organism:
unidentified eubacterium SCB49
NCBI taxonomy Id: 50743
Other names: u. eubacterium SCB49
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.