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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nbaC3-hydroxyanthranilate 3,4 dioxygenase; Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate; Belongs to the 3-HAO family. (178 aa)    
Predicted Functional Partners:
kynU
Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively.
 
  
  0.918
kmo
Putative kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid; Belongs to the aromatic-ring hydroxylase family. KMO subfamily.
 
     0.783
EDM44426.1
Hypothetical protein.
       0.773
EDM45235.1
2-amino-3-carboxylmuconate-6-semialdehyde decarboxylase; COG2159 Predicted metal-dependent hydrolase of the TIM-barrel fold.
 
  
  0.750
EDM45478.1
COG3483 Tryptophan 2,3-dioxygenase (vermilion).
 
  
  0.731
pgi
COG0166 Glucose-6-phosphate isomerase; Belongs to the GPI family.
    
 0.718
EDM44425.1
Hypothetical protein.
       0.714
EDM43103.1
Hypothetical protein; COG0715 ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components.
 
    0.696
EDM45131.1
COG0739 Membrane proteins related to metalloendopeptidases.
    
 0.690
EDM45368.1
Probable nucleotide sugar dehydrogenase; COG1004 Predicted UDP-glucose 6-dehydrogenase.
  
 
 0.677
Your Current Organism:
unidentified eubacterium SCB49
NCBI taxonomy Id: 50743
Other names: u. eubacterium SCB49
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