Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
EDM45245.1UDP-2,3-diacylglucosamine hydrolase; COG2908 Uncharacterized protein conserved in bacteria. (252 aa)    
Predicted Functional Partners:
EDM45042.1
lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
 
  
 0.858
lpxD
UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
  
  
 0.858
EDM44562.1
COG1044 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase.
  
  
 0.840
fabZ
Candidate UDP-3-0-acyl N-acetylglucosamine deacetylase, carbohydrate esterase family 11 protein; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the thioester dehydratase family. FabZ subfamily.
  
   
 0.697
EDM44568.1
COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains.
  
     0.656
EDM45690.1
COG4775 Outer membrane protein/protective antigen OMA87.
  
     0.615
EDM44039.1
Hypothetical protein; COG2317 Zn-dependent carboxypeptidase.
 
     0.613
EDM45689.1
Outer membrane protein, ompH family; COG2825 Outer membrane protein.
  
     0.600
EDM45244.1
Conserved possible 6-pyruvoyl tetrahydrobiopterin synthase; COG0720 6-pyruvoyl-tetrahydropterin synthase.
  
    0.570
EDM45575.1
Hypothetical protein.
  
     0.556
Your Current Organism:
unidentified eubacterium SCB49
NCBI taxonomy Id: 50743
Other names: u. eubacterium SCB49
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.