Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
EDM45248.1Smf protein DNA processing chain A; COG0758 Predicted Rossmann fold nucleotide-binding protein involved in DNA uptake. (380 aa)    
Predicted Functional Partners:
EDM45045.1
Competence protein; COG0658 Predicted membrane metal-binding protein.
 
  
 0.900
EDM44330.1
Putative amidophosphoribosyl-transferase; COG1040 Predicted amidophosphoribosyltransferases.
 
 
 0.894
EDM43135.1
Magnesium chelatase, subunit ChlI; COG0606 Predicted ATPase with chaperone activity.
 
 
 0.825
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
   
 0.757
EDM44354.1
Hypothetical protein; COG0792 Predicted endonuclease distantly related to archaeal Holliday junction resolvase; Belongs to the UPF0102 family.
 
    0.668
EDM43335.1
Hypothetical protein.
 
     0.590
EDM43331.1
comEA protein-related protein; COG1555 DNA uptake protein and related DNA-binding proteins.
 
  
 0.585
EDM45247.1
Hypothetical protein.
       0.582
EDM43796.1
COG2003 DNA repair proteins; Belongs to the UPF0758 family.
  
  
 0.568
EDM44211.1
COG1785 Alkaline phosphatase; Belongs to the alkaline phosphatase family.
  
    0.528
Your Current Organism:
unidentified eubacterium SCB49
NCBI taxonomy Id: 50743
Other names: u. eubacterium SCB49
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