close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EDM45394.1Alginate lyase. (366 aa)    
Predicted Functional Partners:
EDM45395.1
Short-chain dehydrogenase/reductase SDR; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases).
 
     0.913
EDM45396.1
Heparinase II/III-like protein.
 
  
  0.904
EDM45390.1
Poly(beta-D-mannuronate) lyase; COG3210 Large exoproteins involved in heme utilization or adhesion.
 
  
  0.902
EDM45393.1
Natural resistance-associated macrophage protein; COG1914 Mn2+ and Fe2+ transporters of the NRAMP family.
 
     0.894
EDM45398.1
Putative outer membrane protein, probably involved in nutrient binding; COG1629 Outer membrane receptor proteins, mostly Fe transport.
 
 
   0.884
EDM45399.1
Putative outer membrane protein, probably involved in nutrient binding.
 
 
   0.863
guaB
Putative inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
    
  0.677
EDM45400.1
COG2186 Transcriptional regulators.
 
     0.672
EDM45392.1
Gluconokinase and phosphogluconate dehydrogenase (decarboxylating) fusion; COG3265 Gluconate kinase; Belongs to the 6-phosphogluconate dehydrogenase family.
 
     0.655
EDM45402.1
Short-chain dehydrogenase/reductase SDR; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases).
 
     0.633
Your Current Organism:
unidentified eubacterium SCB49
NCBI taxonomy Id: 50743
Other names: u. eubacterium SCB49
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.