close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EDM45417.1COG5009 Membrane carboxypeptidase/penicillin-binding protein. (773 aa)    
Predicted Functional Partners:
EDM45034.1
COG0768 Cell division protein FtsI/penicillin-binding protein 2.
  
 
 0.908
EDM43759.1
COG0768 Cell division protein FtsI/penicillin-binding protein 2.
  
 
 0.887
EDM45035.1
Rod shape-determining protein; COG0772 Bacterial cell division membrane protein; Belongs to the SEDS family.
  
  
 0.844
EDM43763.1
COG0772 Bacterial cell division membrane protein; Belongs to the SEDS family.
  
  
 0.785
EDM45347.1
Hypothetical protein.
    
 0.695
murA
UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily.
  
   
 0.646
mraY
phospho-N-acetylmuramoyl-pentapeptide transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily.
  
     0.615
murF
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily.
  
   
 0.592
EDM44773.1
GTP diphosphokinase (guanosine 3',5'-polyphosphate synthase); In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.
  
    0.592
EDM45351.1
Putative peptidase; COG0739 Membrane proteins related to metalloendopeptidases.
  
     0.584
Your Current Organism:
unidentified eubacterium SCB49
NCBI taxonomy Id: 50743
Other names: u. eubacterium SCB49
Server load: low (34%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.