Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
EDM45427.1COG2318 Uncharacterized protein conserved in bacteria. (170 aa)    
Predicted Functional Partners:
EDM45426.1
COG1253 Hemolysins and related proteins containing CBS domains.
       0.590
EDM43337.1
Hypothetical protein.
  
     0.523
EDM45425.1
Methylated DNA-protein cysteine methyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
       0.514
fumC
Fumarate hydratase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
     
  0.499
EDM43718.1
COG0077 Prephenate dehydratase.
     
  0.499
aroA
Putative 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
     
  0.499
EDM43735.1
Lysyl endopeptidase precursor; COG0495 Leucyl-tRNA synthetase.
  
     0.467
EDM45429.1
COG0113 Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family.
       0.462
EDM45428.1
Cytochrome C biogenesis protein transmembrane region family; COG0526 Thiol-disulfide isomerase and thioredoxins.
       0.442
EDM45424.1
Polysaccharide biosynthesis protein; COG3298 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB.
       0.433
Your Current Organism:
unidentified eubacterium SCB49
NCBI taxonomy Id: 50743
Other names: u. eubacterium SCB49
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