STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EDM45437.1DNA methylase, putative; COG2852 Uncharacterized protein conserved in bacteria. (380 aa)    
Predicted Functional Partners:
EDM45438.1
Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.
 0.995
hemE
Uroporphyrinogen-III decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
  
 
 0.884
EDM45429.1
COG0113 Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family.
  
 0.875
EDM45435.1
Hypothetical protein.
 
     0.736
hemA
glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
  
 
 0.727
EDM45432.1
COG0408 Coproporphyrinogen III oxidase.
     
 0.708
EDM45434.1
Hypothetical protein.
       0.648
EDM45431.1
COG3012 Uncharacterized protein conserved in bacteria.
       0.643
EDM45433.1
COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins.
       0.643
hemL
HemL; COG0001 Glutamate-1-semialdehyde aminotransferase.
  
 
 0.639
Your Current Organism:
unidentified eubacterium SCB49
NCBI taxonomy Id: 50743
Other names: u. eubacterium SCB49
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