Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
EDM45454.1COG1076 DnaJ-domain-containing proteins 1. (241 aa)    
Predicted Functional Partners:
EDM43937.1
Heat shock protein 90; COG0326 Molecular chaperone, HSP90 family.
  
 0.925
EDM43472.1
COG0652 Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family.
   
 0.885
EDM44691.1
COG0652 Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family.
   
 0.885
groL
Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.
  
 0.884
dnaK
Molecular chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
 
 0.883
EDM44004.1
Heat shock protein Hsp70; COG0443 Molecular chaperone; Belongs to the heat shock protein 70 family.
 
 0.882
EDM44932.1
Heat shock protein Hsp70; COG0443 Molecular chaperone.
  
 0.864
EDM44934.1
COG0443 Molecular chaperone; Belongs to the heat shock protein 70 family.
  
 0.864
EDM43022.1
Transketolase; COG1071 Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit.
   
 0.858
ndk
Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.
    
  0.857
Your Current Organism:
unidentified eubacterium SCB49
NCBI taxonomy Id: 50743
Other names: u. eubacterium SCB49
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